Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6733197 | 0.83 | SLC6A2 (0.42) | SLC6A2SLC6A4KCNQ3KCNQ2MAOA | |
| SCHEMBL6732177 | 0.82 | KCNQ3 (0.70) | SLC6A2SLC6A4KCNQ3KCNQ2MEN1 | |
| SCHEMBL6844383 | 0.81 | KCNQ3 (0.49) | SLC6A2SLC6A4KCNQ3KCNQ2MAOA | |
| SCHEMBL6738399 | 0.81 | SLC6A2 (0.39) | SLC6A2SLC6A4KCNQ3KCNQ2MAOA | |
| SCHEMBL6733188 | 0.79 | ALDH1A1 (0.40) | SLC6A2SLC6A4KCNQ3KCNQ2ATM | |
| SCHEMBL5718068 | 0.77 | ATM (0.40) | SLC6A2SLC6A4KCNQ3KCNQ2ATM | |
| SCHEMBL22492062 | 0.77 | KCNQ3 (0.56) | SLC6A2SLC6A4KCNQ3KCNQ2MEN1 | |
| SCHEMBL22492058 | 0.77 | KCNQ3 (0.56) | SLC6A2SLC6A4KCNQ3KCNQ2MEN1 | |
| SCHEMBL12354198 | 0.77 | KCNQ3 (0.56) | SLC6A2SLC6A4KCNQ3KCNQ2MEN1 | |
| SCHEMBL838634 | 0.77 | KCNQ3 (0.56) | SLC6A2SLC6A4KCNQ3KCNQ2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235830-A1 | Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235830-A1 | Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases | CYP46A1, REN, CYP11B2 | SLC6A2 1559/4885SLC6A4 3069/4885CRHBP 2331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.