Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6737836 | 0.92 | PREP (0.39) | ALDH1A1AGTR2CHRM2CHRM1CHRM3 | |
| SCHEMBL5718155 | 0.92 | ALDH1A1 (0.42) | ALDH1A1AGTR2CHRM2CHRM1CHRM3 | |
| SCHEMBL6733285 | 0.82 | KCNQ3 (0.63) | ATMSLC6A2SLC6A4KCNQ3KCNQ2 | |
| SCHEMBL5838740 | 0.79 | PTPRB (0.42) | ALDH1A1SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL6737598 | 0.79 | SLC6A2 (0.45) | ATMSLC6A2SLC6A4KCNQ3KCNQ2 | |
| SCHEMBL20236474 | 0.77 | LTB4R2 (0.50) | ALDH1A1POLBSMN1; SMN2LTB4R2 | |
| SCHEMBL28363637 | 0.76 | ALDH1A1 (0.49) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL20236747 | 0.76 | LTB4R2 (0.49) | ALDH1A1POLBSMN1; SMN2LTB4R2 | |
| SCHEMBL5718068 | 0.76 | ATM (0.40) | ALDH1A1ATMLTB4R2SLC6A2SLC6A4 | |
| SCHEMBL5717911 | 0.76 | KCNQ3 (0.44) | ALDH1A1KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235830-A1 | Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235830-A1 | Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases | CYP46A1, REN, CYP11B2 | ALDH1A1 348/4885AGTR2 100/4885POLB 3746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.