Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23012554 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAKDM1APOLBKDM4E | |
| SCHEMBL5178813 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAKDM1APOLBKDM4E | |
| SCHEMBL22497146 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAKDM1APOLBKDM4E | |
| SCHEMBL1622556 | 0.83 | KDM4E (0.58) | SMN1; SMN2LMNAKDM1APOLBKDM4E | |
| SCHEMBL28121427 | 0.81 | KDM4E (0.56) | SMN1; SMN2LMNAKDM1APOLBKDM4E | |
| SCHEMBL445460 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAKDM1APOLBKDM4E | |
| SCHEMBL19459421 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAKDM1APOLBKDM4E | |
| SCHEMBL2828660 | 0.79 | S1PR4 (0.43) | SMN1; SMN2LMNAKDM1APOLBKDM4E | |
| SCHEMBL20185613 | 0.79 | ALDH1A1 (0.49) | SMN1; SMN2LMNAKDM1APOLBKDM4E | |
| SCHEMBL27690138 | 0.79 | LMNA (0.45) | SMN1; SMN2LMNAKDM1APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444205-B1 | METHOD FOR PRODUCING 2-HALOGEN-PYRIDINE-CARBOXYLIC ACID AMIDES | BASF AG (DE) | 2006-02-01 | — | — | EP | disclosed |
| EP-1444205-A1 | METHOD FOR PRODUCING 2-HALOGEN-PYRIDINE-CARBOXYLIC ACID AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003037868-A1 | METHOD FOR PRODUCING 2-HALOGEN-PYRIDINE-CARBOXYLIC ACID AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-08 | — | — | WO | disclosed |
| EP-0929524-A1 | PYRIDINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND THEIR USE FOR CONTROLLING ANIMAL PESTS AND HARMFUL FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998012179-A1 | PYRIDINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND THEIR USE FOR CONTROLLING ANIMAL PESTS AND HARMFUL FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-26 | — | — | WO | disclosed |