Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2659030 | 0.81 | KDM4E (0.50) | S1PR4TRIM24TRIM33USP2LMNA | |
| SCHEMBL5309545 | 0.81 | TRIM24 (0.40) | S1PR4TRIM24TRIM33USP2GRM4 | |
| SCHEMBL5718211 | 0.79 | SMN1; SMN2 (0.48) | LMNAKDM4ETDP1CYP3A4ALOX12 | |
| SCHEMBL3294621 | 0.75 | LMNA (0.65) | USP2LMNAMETAP2METAP1HDAC6 | |
| SCHEMBL4687124 | 0.75 | BRD4 (0.40) | S1PR4GRM4LMNAKDM4ECYP3A4 | |
| SCHEMBL7695682 | 0.74 | KMT2A (0.45) | LMNATDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL27642657 | 0.74 | CHRM2 (0.40) | S1PR4USP2LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL6970751 | 0.74 | KDM4E (0.47) | USP2KDM4ETDP1CYP3A4ALOX12 | |
| SCHEMBL5429041 | 0.73 | L3MBTL1 (0.51) | S1PR4GRM4KDM4ETDP1POLB | |
| SCHEMBL30524282 | 0.73 | SERPINE1 (0.43) | LMNAKDM4ETDP1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238131-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - Portela & Ca., S.A. (PT) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009084970-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL-PORTELA & COMPANHIA, S.A. (PT) | 2009-07-09 | — | — | WO | disclosed |