Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | GLA | P06280 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 14/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951837 | 0.84 | ALDH1A1 (0.73) | ALDH1A1GLASMN1; SMN2MAPTKDM4E | |
| SCHEMBL13902545 | 0.84 | ALDH1A1 (0.57) | ALDH1A1GLASMN1; SMN2MAPTKDM4E | |
| SCHEMBL18549022 | 0.83 | ALDH1A1 (0.66) | ALDH1A1GLASMN1; SMN2MAPTKDM4E | |
| SCHEMBL14117517 | 0.83 | ALDH1A1 (0.66) | ALDH1A1GLASMN1; SMN2MAPTKDM4E | |
| SCHEMBL9651956 | 0.81 | MAPT (0.68) | ALDH1A1GLASMN1; SMN2MAPTKDM4E | |
| SCHEMBL22609165 | 0.81 | ALDH1A1 (0.57) | ALDH1A1GLASMN1; SMN2MAPTKDM4E | |
| SCHEMBL9003269 | 0.80 | MAPT (0.70) | ALDH1A1GLASMN1; SMN2MAPTKDM4E | |
| SCHEMBL1046139 | 0.80 | MAPT (0.66) | ALDH1A1GLASMN1; SMN2MAPTKDM4E | |
| SCHEMBL5718653 | 0.80 | MAPT (0.65) | ALDH1A1GLASMN1; SMN2MAPTKDM4E | |
| SCHEMBL3476585 | 0.79 | MAPT (0.64) | ALDH1A1GLASMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1298135-B1 | Dyeing composition containing silyl substituted p-aminophenol or p-phenylenediamine | OREAL (FR) | 2006-08-16 | — | — | EP | disclosed |
| US-7018427-B2 | Dyeing composition containing a para-aminophenol or para-phenylenediamine compound substituted with a silane radical | L'OREAL S.A. (FR) | 2006-03-28 | — | — | US | disclosed |
| US-20030150066-A1 | Dyeing composition containing a para-aminophenol or para-phenylenediamine compound substituted with a silane radical | L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | disclosed |
| EP-1298135-A1 | Dyeing composition containing silyl substituted p-aminophenol or p-phenylenediamine | L'OREAL (FR) | 2003-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030150066-A1 | Dyeing composition containing a para-aminophenol or para-phenylenediamine compound substituted with a silane radical | KRT18, CDC73, S100P | ALDH1A1 161/4885GLA 1606/4885SMN1; SMN2 3911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.