SCHEMBL1074601

SCHEMBL1074601

CCc1ccc(-c2c(Cl)nc(C#N)n2S(=O)(=O)N(C)C)cc1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
PTGS2 P35354 3/20 0.33
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP19A1 P11511 2/20 0.32
KMT2A Q03164 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9519740 0.88 PTGS2 (0.39) TSHRPTGS2HPGDSMN1; SMN2KMT2A
Cyazofamid SCHEMBL16180421 0.86 PTGS2 (0.38) TSHRPTGS2SMN1; SMN2KMT2A
Cyazofamid SCHEMBL23804496 0.84 PTGS2 (0.37) TSHRPTGS2SMN1; SMN2KMT2A
SCHEMBL1074589 0.83 PTGS1 (0.41) TSHRPTGS2HPGDSMN1; SMN2KMT2A
SCHEMBL933331 0.83 TSHR (0.34) TSHRPTGS2HPGDSMN1; SMN2CYP2A6
SCHEMBL7095742 0.80 PTGS2 (0.37) PTGS2KMT2A
SCHEMBL6775957 0.79 HPGD (0.30) HPGD
SCHEMBL5718754 0.78 SMN1; SMN2 (0.38) TSHRHPGDSMN1; SMN2KMT2ATP53
SCHEMBL1073894 0.77 PTGS2 (0.46) TSHRPTGS2SMN1; SMN2
Cyazofamid SCHEMBL16910348 0.76 PTGS2 (0.32) TSHRPTGS2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090163567-A1 GERMICIDE COMPOSITION FOR AGRICULTURAL AND GARDENING APPLICATIONS AND METHOD FOR CONTROLLING PLANT DISEASE ISHIHARA SANGYO KAISHA, LTD (JP) 2009-06-25 US claimed
EP-1952689-A1 GERMICIDE COMPOSITION FOR AGRICULTURAL AND GARDENING APPLICATIONS AND METHOD FOR CONTROLLING PLANT DISEASE ISHIHARA SANGYO KAISHA, LTD. (JP) 2008-08-06 EP claimed
US-6713500-B2 IMIDAZOLE DERIVATIVES; FOR CONTROLLING COCCIDIOSIS ISHIHARA SANGYO KAISHA LTD. (JP) 2004-03-30 US claimed
US-8741859-B2 Fungicide composition for agriculture and horticulture and method for preventing plant diseases ISHIHARA SANGYO KAISHA, LTD (JP) 2014-06-03 US disclosed
US-8580288-B2 Agricultural or horticultural fungicide composition and its use for controlling plant pathogens ISHIHARA SANGYO KAISHA, LTD (JP) 2013-11-12 US disclosed
EP-2617287-A1 Germicide composition for agricultural and gardening applications and method for controlling plant disease ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-07-24 EP disclosed
US-20120108644-A1 AGRICULTURAL OR HORTICULTURAL FUNGICIDE COMPOSITION AND ITS USE FOR CONTROLLING PLANT PATHOGENS ISHIHARA SANGYO KAISHA, LTD. (JP) 2012-05-03 US disclosed
US-20110028419-A1 FUNGICIDE COMPOSITION FOR AGRICULTURE AND HORTICULTURE AND METHOD FOR PREVENTING PLANT DISEASES ISHIHARA SANGYO KAISHA, LTD (JP) 2011-02-03 US disclosed
EP-1769679-B1 BACTERICIDAL COMPOSITION FOR AGRICULTURAL OR HORTICULTURAL USE AND METHOD OF CONTROLLING PLANT DISEASE ISHIHARA SANGYO KAISHA (JP) 2011-01-19 EP disclosed
US-7851497-B2 Bactericidal composition for agricultural or horticultural use and method of controlling plant disease ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-12-14 US disclosed
US-20090163567-A1 GERMICIDE COMPOSITION FOR AGRICULTURAL AND GARDENING APPLICATIONS AND METHOD FOR CONTROLLING PLANT DISEASE ISHIHARA SANGYO KAISHA, LTD (JP) 2009-06-25 US disclosed
EP-1417887-A1 Pesticidal composition and method for controlling pests ISHIHARA SANGYO KAISHA, LTD. (JP) 2004-05-12 EP disclosed
US-6713500-B2 IMIDAZOLE DERIVATIVES; FOR CONTROLLING COCCIDIOSIS ISHIHARA SANGYO KAISHA LTD. (JP) 2004-03-30 US disclosed
EP-1316254-A1 Pesticidal composition and method for controlling pests ISHIHARA SANGYO KAISHA, LTD. (JP) 2003-06-04 EP disclosed
US-20030100586-A1 Agent for controlling animal diseases caused by parasites ISHIHARA SANGYO KAISHA LTD. (JP) 2003-05-29 US disclosed
EP-1194039-B1 PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING PESTS ISHIHARA SANGYO KAISHA (JP) 2003-05-21 EP disclosed
EP-0979034-B1 COMPOSITION FOR CONTROLLING HARMFUL BIO-ORGANISMS AND METHOD FOR CONTROLLING HARMFUL BIO-ORGANISMS USING THE SAME ISHIHARA SANGYO KAISHA (JP) 2003-02-26 EP disclosed
US-20020142021-A1 Composition for controlling harmful bio-organisms and method for controlling harmful bio-organisms using the same ISHIHARA SANGYO KAISHA, LTD. 2002-10-03 US disclosed
EP-1211245-A1 AGENTS FOR CONTROLLING ANIMAL DISEASES CAUSED BY PARASITES ISHIHARA SANGYO KAISHA, LTD. (JP) 2002-06-05 EP disclosed
US-6375965-B1 Composition for controlling harmful bio-organisms and method for controlling harmful bio-organisms using the same ISHIHARA SANGYO KAISHA, LTD. (JP) 2002-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108644-A1 AGRICULTURAL OR HORTICULTURAL FUNGICIDE COMPOSITION AND ITS USE FOR CONTROLLING PLANT PATHOGENS CYP51A1, DHFR, PFAS TSHR 4244/4885PTGS2 3969/4885HPGD 3283/4885
US-20030100586-A1 Agent for controlling animal diseases caused by parasites CLIC1, CLIC4, H1-4 TSHR 2090/4885PTGS2 1898/4885HPGD 4313/4885
US-20020142021-A1 Composition for controlling harmful bio-organisms and method for controlling harmful bio-organisms using the same PPA1, IPMK, ERG28 TSHR 4405/4885PTGS2 4330/4885HPGD 4461/4885
US-20090163567-A1 GERMICIDE COMPOSITION FOR AGRICULTURAL AND GARDENING APPLICATIONS AND METHOD FOR CONTROLLING PLANT DISEASE AGL, GMDS, MGAM TSHR 1664/4885PTGS2 2421/4885HPGD 1827/4885
US-20110028419-A1 FUNGICIDE COMPOSITION FOR AGRICULTURE AND HORTICULTURE AND METHOD FOR PREVENTING PLANT DISEASES BROX, PRDX6, GLRX3 TSHR 3180/4885PTGS2 3960/4885HPGD 2818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.