Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.83 |
| ▸ | LMNA | P02545 | 5/20 | 0.83 |
| ▸ | TSHR | P16473 | 5/20 | 0.83 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5719592 | 0.90 | ALDH1A1 (0.76) | ALDH1A1LMNATSHRNPSR1MAPK1 | |
| SCHEMBL5719356 | 0.75 | ALDH1A1 (0.55) | ALDH1A1LMNATSHRNPSR1MAPK1 | |
| SCHEMBL19374800 | 0.75 | TSHR (0.81) | ALDH1A1LMNATSHRNPSR1MAPK1 | |
| SCHEMBL554778 | 0.74 | DPP4 (0.87) | ALDH1A1LMNATSHRNPSR1MAPK1 | |
| SCHEMBL5719291 | 0.73 | LMNA (0.53) | ALDH1A1LMNATSHRNPSR1MAPK1 | |
| SCHEMBL5642832 | 0.73 | DPP4 (0.80) | ALDH1A1LMNATSHRNPSR1MAPK1 | |
| SCHEMBL8339602 | 0.73 | ALDH1A1 (0.81) | ALDH1A1LMNATSHRNPSR1MAPK1 | |
| SCHEMBL5719693 | 0.73 | LMNA (0.52) | ALDH1A1LMNATSHRNPSR1MAPK1 | |
| SCHEMBL5642270 | 0.73 | DPP4 (0.68) | ALDH1A1LMNATSHRNPSR1SMN1; SMN2 | |
| SCHEMBL6425261 | 0.72 | ALDH1A1 (0.52) | ALDH1A1LMNATSHRNPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1338595-B1 | Xanthine derivatives as DPP-IV inhibitors | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | disclosed |