Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508988 | 0.82 | LMNA (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL5662522 | 0.82 | LMNA (0.50) | LMNARAB9APOLBL3MBTL1ADRB2 | |
| SCHEMBL8670088 | 0.81 | LMNA (0.47) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL7567777 | 0.79 | LMNA (0.60) | LMNAPTGS1POLBL3MBTL1ADRB2 | |
| SCHEMBL2162271 | 0.79 | LMNA (0.55) | LMNAHIF1ATSHRL3MBTL1ADRB2 | |
| SCHEMBL5599025 | 0.78 | LMNA (0.46) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL29172647 | 0.78 | CA1 (0.48) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL6898511 | 0.78 | LMNA (0.63) | LMNAPTGS1HIF1ATSHRL3MBTL1 | |
| SCHEMBL10399389 | 0.78 | RECQL (0.59) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL14461599 | 0.78 | LMNA (0.53) | LMNACYP1A2PTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692279-A4 | PRESERVATIVE-CONTAINING VIRUS FORMULATIONS | MERCK & CO INC (US) | 2006-12-27 | — | — | EP | disclosed |
| EP-1692279-A2 | PRESERVATIVE-CONTAINING VIRUS FORMULATIONS | Merck & Co., Inc. (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005052116-A2 | PRESERVATIVE-CONTAINING VIRUS FORMULATIONS | MERCK & CO., INC. (US) | 2005-06-09 | — | — | WO | disclosed |