Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720117 | 0.83 | NLRP3 (0.49) | TDP1POLBRAB9ACYP2C19ALOX15 | |
| SCHEMBL5720204 | 0.71 | CYP2C19 (0.56) | POLBCYP2C19TSHRALDH1A1ITGA4 | |
| SCHEMBL18415577 | 0.69 | HTT (0.58) | TDP1CYP2C19ALOX15TSHRHIF1A | |
| SCHEMBL6070485 | 0.69 | HTT (0.55) | POLBCYP2C19HTTNPSR1LMNA | |
| SCHEMBL4338457 | 0.68 | CYP2C19 (0.54) | TDP1POLBRAB9ACYP2C19ALOX15 | |
| SCHEMBL17873434 | 0.67 | CYP2C19 (0.50) | TDP1POLBCYP2C19ALOX15TSHR | |
| SCHEMBL7824235 | 0.67 | ALDH1A1 (0.60) | TDP1CYP2C19ALOX15TSHRHIF1A | |
| SCHEMBL27505319 | 0.67 | ALDH1A1 (0.60) | TDP1CYP2C19ALOX15TSHRHIF1A | |
| SCHEMBL7824232 | 0.67 | ALDH1A1 (0.60) | TDP1CYP2C19ALOX15TSHRHIF1A | |
| SCHEMBL17873435 | 0.67 | CYP2C19 (0.50) | TDP1POLBCYP2C19ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668007-A1 | DIOXOLANE DERIVATIVES AS CELL ADHESION INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005026163-A1 | DIOXOLANE DERIVATIVES AS CELL ADHESION INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-24 | — | — | WO | disclosed |