Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720008 | 0.83 | TDP1 (0.50) | NLRP3TDP1POLBRAB9ATSHR | |
| SCHEMBL85617 | 0.78 | ALDH1A1 (0.46) | TDP1POLBRAB9AHTTCYP2C19 | |
| SCHEMBL85862 | 0.76 | TSHR (0.46) | TSHRALOX15KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7209322 | 0.76 | TSHR (0.46) | TSHRALOX15KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7203762 | 0.76 | TSHR (0.46) | TSHRALOX15KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11171183 | 0.72 | NLRP3 (0.52) | NLRP3TDP1POLBRAB9ATSHR | |
| SCHEMBL5720126 | 0.72 | TSHR (0.44) | TSHRHTTCYP2C19KDM4EALDH1A1 | |
| SCHEMBL5720266 | 0.72 | HSD17B10 (0.40) | RAB9ATSHRALOX15CAPN1KDM4E | |
| SCHEMBL85522 | 0.70 | PPM1B (0.46) | POLBTSHRALDH1A1 | |
| SCHEMBL5719777 | 0.70 | PPM1B (0.46) | POLBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668007-A1 | DIOXOLANE DERIVATIVES AS CELL ADHESION INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005026163-A1 | DIOXOLANE DERIVATIVES AS CELL ADHESION INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-24 | — | — | WO | disclosed |