Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833670 | 0.92 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10CCR1 | |
| Diphenylmethanol SCHEMBL8076973 | 0.86 | L3MBTL1 (0.53) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| Diphenylmethanol SCHEMBL9185711 | 0.85 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10CCR1 | |
| Diphenylmethanol SCHEMBL8081652 | 0.85 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10CCR1 | |
| SCHEMBL5720159 | 0.83 | MAPT (0.43) | KDM4EALDH1A1HPGDHSD17B10CCR1 | |
| Diphenylmethanol SCHEMBL8075180 | 0.82 | HTT (0.51) | KDM4EALDH1A1HPGDHSD17B10CCR1 | |
| Diphenylmethanol SCHEMBL8081675 | 0.82 | HTT (0.43) | KDM4EALDH1A1HPGDHSD17B10CCR2 | |
| Diphenylmethanol SCHEMBL8067095 | 0.82 | HTT (0.47) | KDM4EALDH1A1HPGDHSD17B10CCR2 | |
| Diphenylmethanol SCHEMBL8075196 | 0.79 | CCR2 (0.75) | CCR1CCR2CYP2C19 | |
| Diphenylmethanol SCHEMBL8067191 | 0.78 | CCR2 (0.77) | CCR1CCR2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841910-A4 | INHIBITION OF CoA-INDEPENDENT TRANSACYLASE AND APOPTOSIS | SMITHKLINE BEECHAM CORP (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-0799198-B1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2000-08-30 | — | — | EP | disclosed |
| EP-0841910-A1 | INHIBITION OF CoA-INDEPENDENT TRANSACYLASE AND APOPTOSIS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-05-20 | — | — | EP | disclosed |
| EP-0799198-A4 | — | — | 1997-10-15 | — | — | EP | disclosed |
| EP-0799198-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-08 | — | — | EP | disclosed |
| WO-1997004765-A1 | INHIBITION OF CoA-INDEPENDENT TRANSACYLASE AND APOPTOSIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-02-13 | — | — | WO | disclosed |
| US-5545669-A | Anti-inflammatory compounds | SMITHKLINE BEECHAM CORPORATION | 1996-08-13 | — | — | US | disclosed |
| WO-1995033461-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |
| WO-1995033460-A1 | ANTI-INFLAMMATORY COUMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |
| US-5447957-A | Anti-inflammatory compounds | SMITHKLINE BEECHAM CORP. (US) | 1995-09-05 | — | — | US | disclosed |