Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylmethanol SCHEMBL9185711 | 1.00 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL8077059 | 0.91 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL9185703 | 0.89 | L3MBTL1 (0.41) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL8081645 | 0.85 | L3MBTL1 (0.43) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| Diphenylmethanol SCHEMBL5720164 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| Diphenylmethanol SCHEMBL9188471 | 0.81 | GRIK1 (0.45) | ALDH1A1L3MBTL1MAPTLMNAATM | |
| SCHEMBL9189926 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| Diphenylmethanol SCHEMBL8076937 | 0.81 | CCR2 (0.55) | KCNQ3KCNQ2CCR1CCR2 | |
| SCHEMBL8077096 | 0.80 | CFTR (0.57) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| Diphenylmethanol SCHEMBL8076973 | 0.79 | L3MBTL1 (0.53) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799198-B1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2000-08-30 | — | — | EP | disclosed |
| US-5545669-A | Anti-inflammatory compounds | SMITHKLINE BEECHAM CORPORATION | 1996-08-13 | — | — | US | disclosed |
| US-5447957-A | Anti-inflammatory compounds | SMITHKLINE BEECHAM CORP. (US) | 1995-09-05 | — | — | US | disclosed |