Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432586 | 0.83 | L3MBTL1 (0.49) | L3MBTL1MAPTLMNAATMRAB9A | |
| SCHEMBL9118710 | 0.83 | MAPT (0.53) | L3MBTL1MAPTLMNAATMRAB9A | |
| SCHEMBL8740742 | 0.81 | MAPT (0.54) | L3MBTL1MAPTLMNAATMRAB9A | |
| SCHEMBL8077059 | 0.79 | ALDH1A1 (0.51) | L3MBTL1MAPTLMNAATMRAB9A | |
| SCHEMBL11706565 | 0.78 | MAPT (0.72) | L3MBTL1MAPTLMNAATMRAB9A | |
| SCHEMBL8077096 | 0.77 | CFTR (0.57) | L3MBTL1MAPTLMNAATMRAB9A | |
| SCHEMBL8935331 | 0.74 | L3MBTL1 (0.69) | L3MBTL1MAPTLMNAATMRAB9A | |
| SCHEMBL9241009 | 0.74 | L3MBTL1 (0.46) | L3MBTL1MAPTLMNAATMRAB9A | |
| SCHEMBL9118572 | 0.73 | NPC1 (0.42) | MAPTLMNAATMRAB9ANPSR1 | |
| SCHEMBL5720192 | 0.73 | L3MBTL1 (0.43) | L3MBTL1MAPTLMNAATMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841910-A4 | INHIBITION OF CoA-INDEPENDENT TRANSACYLASE AND APOPTOSIS | SMITHKLINE BEECHAM CORP (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-0841910-A1 | INHIBITION OF CoA-INDEPENDENT TRANSACYLASE AND APOPTOSIS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997004765-A1 | INHIBITION OF CoA-INDEPENDENT TRANSACYLASE AND APOPTOSIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-02-13 | — | — | WO | disclosed |