Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | UBE2N | P61088 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8740742 | 0.91 | MAPT (0.54) | MAPTL3MBTL1LMNAATMRAB9A | |
| SCHEMBL5720198 | 0.83 | L3MBTL1 (0.49) | MAPTL3MBTL1LMNAATMRAB9A | |
| SCHEMBL11706565 | 0.82 | MAPT (0.72) | MAPTL3MBTL1LMNAATMRAB9A | |
| SCHEMBL8432586 | 0.80 | L3MBTL1 (0.49) | MAPTL3MBTL1LMNAATMRAB9A | |
| SCHEMBL8077059 | 0.80 | ALDH1A1 (0.51) | MAPTL3MBTL1LMNAATMRAB9A | |
| SCHEMBL8077096 | 0.78 | CFTR (0.57) | MAPTL3MBTL1LMNAATMRAB9A | |
| SCHEMBL8935331 | 0.78 | L3MBTL1 (0.69) | MAPTL3MBTL1LMNAATMRAB9A | |
| SCHEMBL21791773 | 0.75 | MAPT (0.42) | MAPTL3MBTL1LMNAATMRAB9A | |
| SCHEMBL11703208 | 0.74 | MAPT (0.67) | MAPTL3MBTL1LMNAATMRAB9A | |
| SCHEMBL3277810 | 0.73 | MAPT (0.52) | MAPTL3MBTL1LMNAATMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033458-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |