Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11607902 | 0.83 | TSHR (0.35) | TSHRALDH1A1KIF11MAPK1PGK1 | |
| SCHEMBL4219815 | 0.81 | TSHR (0.58) | TSHRALDH1A1CYP1A2PTPN1KCNN4 | |
| SCHEMBL11234202 | 0.79 | PGK1 (0.44) | TSHRALDH1A1CYP1A2CA1CA2 | |
| Trifluoromethylbenzene SCHEMBL6439041 | 0.79 | TSHR (0.82) | TSHRALDH1A1CYP1A2PTPN1KCNN4 | |
| SCHEMBL10885277 | 0.79 | ALDH1A1 (0.55) | TSHRALDH1A1CYP1A2PTPN1KCNN4 | |
| Trifluoromethylbenzene SCHEMBL31493124 | 0.78 | TSHR (0.93) | TSHRALDH1A1CYP1A2PTPN1KCNN4 | |
| SCHEMBL7638465 | 0.77 | TSHR (0.60) | TSHRALDH1A1CYP1A2PTPN1KCNN4 | |
| SCHEMBL10601694 | 0.77 | TSHR (0.60) | TSHRALDH1A1CYP1A2PTPN1KCNN4 | |
| SCHEMBL7644764 | 0.77 | TSHR (0.52) | TSHRALDH1A1CYP1A2PTPN1KCNN4 | |
| SCHEMBL7967046 | 0.77 | TSHR (0.52) | TSHRALDH1A1CYP1A2PTPN1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670694-A | AMMOXIDATION OF CORRESPONDING TOLUENE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | claimed |
| EP-0731087-A1 | Process for the preparation of 2,4-dichloro-5-fluorobenzonitrile and 2,6-dichloro-3-fluorobenzonitrile | BAYER AG (DE) | 1996-09-11 | — | — | EP | claimed |
| US-4059610-A | Process for preparing isocyanic acid derivatives | KAO SOAP CO., LTD. (JA) | 1977-11-22 | — | — | US | claimed |
| JP-8245542-A | — | — | None | — | — | JP | disclosed |
| CN-114478390-A | Titanium-based acidic ionic liquid, preparation method and application | 西安近代化学研究所 | 2022-05-13 | — | — | CN | disclosed |
| US-20090036718-A1 | USE OF A COMPOSITION OF AN IONIC NATURE AS A SUBSTITUTION REAGENT, A COMPOSITION CONSTITUTING A FLUORINATION REAGENT AND A METHOD USING SAME | RHODIA CHIMIE (FR) | 2009-02-05 | — | — | US | disclosed |
| US-7393980-B2 | Use of a composition of an ionic nature as a substrate reagent, a composition constituting a fluorination reagent and a method using same | RHODIA CHIMIE (FR) | 2008-07-01 | — | — | US | disclosed |
| EP-1072576-B1 | FLUORINATING AGENT, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | MITSUI CHEMICALS INC (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6417361-B1 | HYDROGEN FLUORIDE AND N,N'-DIALKYLCYCLIC UREA COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2002-07-09 | — | — | US | disclosed |
| CN-1294568-A | Fluorinating agent, process for producing same, and use thereof | MITSUI CHEMICALS INC (JP) | 2001-05-09 | — | — | CN | disclosed |
| EP-1072576-A1 | FLUORINATING AGENT, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2001-01-31 | — | — | EP | disclosed |
| US-4310680-A | METAL OR METAL COMPOUND CATALYST | DYNAMIT NOBEL AG (DE) | 1982-01-12 | — | — | US | disclosed |
| EP-0031436-A2 | A method for the cleavage of siloxanes | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1981-07-08 | — | — | EP | disclosed |
| EP-0009787-A2 | Process for the monohalogenation of alkylbenzenes in alpha position | BAYER AG (DE) | 1980-04-16 | — | — | EP | disclosed |
| US-4183873-A | WITH HYDROGEN FLUORIDE IN THE PRESENCE OF MOLYBDENUM PENTACHLORIDE CATALYST | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-01-15 | — | — | US | disclosed |
| US-4130594-A | Liquid phase fluorination process | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1978-12-19 | — | — | US | disclosed |
| US-4129602-A | TANTALUM, NIOBIUM OR RHENIUM PENTAFLUORIDE OR PENTACHLORIDE CATALYST | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1978-12-12 | — | — | US | disclosed |
| US-4098832-A | FLUORINATION PROCESS CATALYSED BY MOLYBDENUM PENTACHLORIDE | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1978-07-04 | — | — | US | disclosed |
| US-4080392-A | CONVERTING THE CORRESPONDING TRICHLOROMETHYL COMPOUND WITH HYDROGEN FLUORIDE, ANTIMONY PENTACHLORIDE CATALYST | LONZA LTD. (CH) | 1978-03-21 | — | — | US | disclosed |
| US-4059610-A | Process for preparing isocyanic acid derivatives | KAO SOAP CO., LTD. (JA) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036718-A1 | USE OF A COMPOSITION OF AN IONIC NATURE AS A SUBSTITUTION REAGENT, A COMPOSITION CONSTITUTING A FLUORINATION REAGENT AND A METHOD USING SAME | H1-10, H1-3, H1-0 | TSHR 176/4885ALDH1A1 3624/4885CYP1A2 1805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.