SCHEMBL5720573

SCHEMBL5720573

COc1cc(/N=N/c2ccc(N)cc2)ccc1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
MAPT P10636 5/20 0.52
RAB9A P51151 5/20 0.52
TDP1 Q9NUW8 4/20 0.52
NPC1 O15118 4/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
ALDH1A1 P00352 5/20 0.52
CYP3A4 P08684 2/20 0.52
TSHR P16473 1/20 0.52
HSD17B10 Q99714 1/20 0.52
PTGS2 P35354 2/20 0.50
PTGS1 P23219 3/20 0.49
GAA P10253 2/20 0.47
HTT P42858 2/20 0.45
PKM P14618 2/20 0.45
HSP90AA1 P07900 1/20 0.45
APP P05067 1/20 0.42
HTR3E A5X5Y0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5720576 1.00 MEN1 (0.52) MEN1KMT2AMAPTRAB9ATDP1
SCHEMBL5720649 0.92 ALDH1A1 (0.59) MEN1KMT2AMAPTRAB9ATDP1
SCHEMBL5720651 0.92 ALDH1A1 (0.59) MEN1KMT2AMAPTRAB9ATDP1
SCHEMBL30287633 0.87 MEN1 (0.56) MEN1KMT2AMAPTRAB9ATDP1
SCHEMBL16684224 0.87 MAPT (0.56) MEN1KMT2AMAPTRAB9ATDP1
SCHEMBL28543488 0.87 ALDH1A1 (0.61) MEN1KMT2AMAPTRAB9ATDP1
SCHEMBL4537233 0.87 MEN1 (0.56) MEN1KMT2AMAPTRAB9ATDP1
SCHEMBL4537236 0.87 MEN1 (0.56) MEN1KMT2AMAPTRAB9ATDP1
SCHEMBL28543485 0.87 ALDH1A1 (0.61) MEN1KMT2AMAPTRAB9ATDP1
SCHEMBL11791506 0.86 ALDH1A1 (0.48) MEN1KMT2AMAPTRAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9834644-B1 Photomechanically active copolyimides derived from an azobenzenediamine, a rigid dianhydride, and a flexible dianhydride THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2017-12-05 US claimed
US-9085661-B1 Photomechanically active copolyimides derived from an azobenzenediamine, a rigid dianhydride, and a flexible dianhydride THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2015-07-21 US claimed
US-9834644-B1 Photomechanically active copolyimides derived from an azobenzenediamine, a rigid dianhydride, and a flexible dianhydride THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2017-12-05 US disclosed
US-9085661-B1 Photomechanically active copolyimides derived from an azobenzenediamine, a rigid dianhydride, and a flexible dianhydride THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2015-07-21 US disclosed
EP-1345992-B1 DISAZO DYES, AND COPPER COMPLEXES THEREOF, FOR DYEING PAPER CIBA SC HOLDING AG (CH) 2006-07-05 EP disclosed
US-5288294-A Lightfastness CIBA-GEIGY CORPORATION (US) 1994-02-22 US disclosed
US-5112989-A Process for producing unsaturated mono and dicarboxylic acid imide compound MATSUSHITA ELECTRIC WORKS LTD. (JP) 1992-05-12 US disclosed
EP-0387381-A1 Process for producing unsaturated dicarboxylic acid imide compound MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1990-09-19 EP disclosed
US-4093613-A Trisazo pigments containing two barbituric acid coupling components CIBA-GEIGY CORPORATION (US) 1978-06-06 US disclosed
US-4043999-A Methyl or methoxy substituted iminoisoindolinone pigments CIBA-GEIGY CORPORATION (US) 1977-08-23 US disclosed