SCHEMBL5720649

SCHEMBL5720649

COc1cc(/N=N/c2ccc(N)c(OC)c2)ccc1N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
CYP3A4 P08684 4/20 0.59
TDP1 Q9NUW8 3/20 0.59
TSHR P16473 2/20 0.59
HSD17B10 Q99714 1/20 0.59
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
GAA P10253 3/20 0.51
MAPT P10636 2/20 0.51
PTGS1 P23219 3/20 0.50
PTGS2 P35354 2/20 0.50
HTT P42858 1/20 0.48
APP P05067 3/20 0.47
HTR3E A5X5Y0 1/20 0.47
HTR3B O95264 1/20 0.47
HTR3A P46098 1/20 0.47
HTR3D Q70Z44 1/20 0.47
HTR3C Q8WXA8 1/20 0.47
ADRA2B P18089 1/20 0.46
L3MBTL1 Q9Y468 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5720651 1.00 ALDH1A1 (0.59) ALDH1A1CYP3A4TDP1TSHRHSD17B10
SCHEMBL5720573 0.92 MEN1 (0.52) ALDH1A1CYP3A4TDP1TSHRHSD17B10
SCHEMBL5720576 0.92 MEN1 (0.52) ALDH1A1CYP3A4TDP1TSHRHSD17B10
SCHEMBL4537233 0.91 MEN1 (0.56) ALDH1A1CYP3A4TDP1TSHRHSD17B10
SCHEMBL4537236 0.91 MEN1 (0.56) ALDH1A1CYP3A4TDP1TSHRHSD17B10
SCHEMBL28543485 0.91 ALDH1A1 (0.61) ALDH1A1CYP3A4TDP1TSHRHSD17B10
SCHEMBL16684224 0.91 MAPT (0.56) ALDH1A1CYP3A4TDP1TSHRHSD17B10
SCHEMBL28543488 0.91 ALDH1A1 (0.61) ALDH1A1CYP3A4TDP1TSHRHSD17B10
SCHEMBL30287633 0.91 MEN1 (0.56) ALDH1A1CYP3A4TDP1TSHRHSD17B10
SCHEMBL11791506 0.89 ALDH1A1 (0.48) ALDH1A1CYP3A4TDP1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060229440-A1 Disazo dyes, and copper complexes thereof, for dyeing paper KASER ADOLF 2006-10-12 US disclosed
US-7078497-B2 Disazo dyes, and copper complexes thereof, for dyeing paper CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-07-18 US disclosed
EP-1345992-B1 DISAZO DYES, AND COPPER COMPLEXES THEREOF, FOR DYEING PAPER CIBA SC HOLDING AG (CH) 2006-07-05 EP disclosed
EP-1345993-B1 USE OF COPPER COMPLEXES OF DISAZO DYES FOR DYEING NATURAL AND SYNTHETIC MATERIAL CIBA SC HOLDING AG (CH) 2006-03-08 EP disclosed
US-20040063920-A1 Disazo dyes, and copper complexes thereof, for dyeing paper CIBA SPECIALTY CHEMICALS CORP. 2004-04-01 US disclosed
EP-1345992-A2 DISAZO DYES, AND COPPER COMPLEXES THEREOF, FOR DYEING PAPER Ciba SC Holding AG (CH) 2003-09-24 EP disclosed
WO-2002053649-A2 DISAZO DYES, AND COPPER COMPLEXES THEREOF, FOR DYEING PAPER CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-07-11 WO disclosed
US-4594410-A Azo compounds containing both sulfo groups and basic or cationic groups which compounds are in metal-free or 1:1 metal complex form SANDOZ LTD. (CH) 1986-06-10 US disclosed
EP-0051041-B1 BASIC OR CATIONIC SULPHONIC ACID GROUP-CONTAINING AZO COMPOUNDS, THEIR SYNTHESIS AND THEIR USE IN DYEING SUBSTRATES CONTAINING PAPER OR COTTON AS WELL AS DYESTUFF PREPARATIONS THEREOF SANDOZ AG (CH) 1984-08-01 EP disclosed
EP-0051041-A1 Basic or cationic sulphonic acid group-containing azo compounds, their synthesis and their use in dyeing substrates containing paper or cotton as well as dyestuff preparations thereof SANDOZ AG (CH) 1982-05-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060229440-A1 Disazo dyes, and copper complexes thereof, for dyeing paper AOC1, SOD1, AOC3 ALDH1A1 137/4885CYP3A4 495/4885TDP1 2740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.