SCHEMBL4537236

SCHEMBL4537236

COc1cc(N=Nc2ccccc2)ccc1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.56
KMT2A Q03164 5/20 0.56
MAPT P10636 5/20 0.55
GAA P10253 3/20 0.55
ALDH1A1 P00352 6/20 0.50
TDP1 Q9NUW8 5/20 0.50
CYP3A4 P08684 4/20 0.50
TSHR P16473 3/20 0.50
HSD17B10 Q99714 1/20 0.50
RAB9A P51151 3/20 0.48
PTGS1 P23219 2/20 0.48
HTT P42858 2/20 0.48
PKM P14618 1/20 0.48
ADRA2B P18089 1/20 0.48
L3MBTL1 Q9Y468 4/20 0.47
PTGS2 P35354 2/20 0.47
NPC1 O15118 2/20 0.47
HSP90AA1 P07900 1/20 0.47
APP P05067 1/20 0.45
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30287633 1.00 MEN1 (0.56) MEN1KMT2AMAPTGAAALDH1A1
SCHEMBL4537233 1.00 MEN1 (0.56) MEN1KMT2AMAPTGAAALDH1A1
SCHEMBL5720649 0.91 ALDH1A1 (0.59) MEN1KMT2AMAPTGAAALDH1A1
SCHEMBL5720651 0.91 ALDH1A1 (0.59) MEN1KMT2AMAPTGAAALDH1A1
SCHEMBL5720576 0.87 MEN1 (0.52) MEN1KMT2AMAPTGAAALDH1A1
SCHEMBL5720573 0.87 MEN1 (0.52) MEN1KMT2AMAPTGAAALDH1A1
SCHEMBL28543488 0.86 ALDH1A1 (0.61) MEN1KMT2AMAPTGAAALDH1A1
SCHEMBL16684224 0.86 MAPT (0.56) MEN1KMT2AMAPTGAAALDH1A1
SCHEMBL28543485 0.86 ALDH1A1 (0.61) MEN1KMT2AMAPTGAAALDH1A1
SCHEMBL11130914 0.85 KMT2A (0.78) MEN1KMT2AMAPTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040194234-A1 Dyed and/or printed non-woven fabric CARL FREUDENBERG KG (DE) 2004-10-07 US claimed
CN-108273478-B Formaldehyde removal composition and product 李怀玉 2021-03-02 CN disclosed
US-10695830-B2 Copper powder, copper paste using same, conductive coating material, conductive sheet, and method for producing copper powder SUMITOMO METAL MINING CO., LTD. (JP) 2020-06-30 US disclosed
US-10654101-B2 Silver-coated copper powder, copper paste using same, conductive coating material, conductive sheet, and method for producing silver-coated copper powder SUMITOMO METAL MINING CO., LTD. (JP) 2020-05-19 US disclosed
US-20180154436-A1 SILVER-COATED COPPER POWDER, COPPER PASTE USING SAME, CONDUCTIVE COATING MATERIAL, CONDUCTIVE SHEET, AND METHOD FOR PRODUCING SILVER-COATED COPPER POWDER SUMITOMO METAL MINING CO., LTD. (JP) 2018-06-07 US disclosed
US-20180111190-A1 COPPER POWDER, COPPER PASTE USING SAME, CONDUCTIVE COATING MATERIAL, CONDUCTIVE SHEET, AND METHOD FOR PRODUCING COPPER POWDER SUMITOMO METAL MINING CO., LTD. (JP) 2018-04-26 US disclosed
EP-3296042-A1 SILVER-COATED COPPER POWDER, COPPER PASTE USING SAME, CONDUCTIVE COATING MATERIAL, CONDUCTIVE SHEET, AND METHOD FOR PRODUCING SILVER-COATED COPPER POWDER Sumitomo Metal Mining Co., Ltd. (JP) 2018-03-21 EP disclosed
EP-3296041-A1 COPPER POWDER, COPPER PASTE USING SAME, CONDUCTIVE COATING MATERIAL, CONDUCTIVE SHEET, AND METHOD FOR PRODUCING COPPER POWDER Sumitomo Metal Mining Co., Ltd. (JP) 2018-03-21 EP disclosed
EP-2846788-A1 USE OF COMPOUNDS FOR THE TREATMENT OF PAIN Akron Molecules AG (AT) 2015-03-18 EP disclosed
US-20140349969-A1 COMPOUNDS AND METHODS FOR TREATING PAIN AKRON MOLECULES AG (AT) 2014-11-27 US disclosed
US-4128545-A DISPERSE, POLYESTER BASF AKTIENGESELLSCHAFT (DE) 1978-12-05 US disclosed
US-4113720-A Disperse azo dye with diaminopyrimidine coupling component BASF AKTIENGESELLSCHAFT (DE) 1978-09-12 US disclosed
US-4083684-A AZO DYES, WASHFASTNESS, PHOTOSTABILITY, SOLVENT RESISTANCE BASF AKTIENGESELLSCHAFT (DT) 1978-04-11 US disclosed
US-4065254-A DIAZO DYES, LEATHER, COTTON, WOOL CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed
US-4056367-A DYEING PETROLEUM, INKS, FATS, WAXES, PLASTICS PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-11-01 US disclosed
US-4042578-A POLYESTERS BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1977-08-16 US disclosed
US-4041025-A FOR HYDROPHOBIC FIBERS SUCH AS POLYESTERS, YELLOW TO BLUE-GREEN SHADES BASF AKTIENGESELLSCHAFT (DT) 1977-08-09 US disclosed
US-4016152-A SUITABLE FOR DYEING POLYESTERS BASF AKTIENGESELLSCHAFT (DT) 1977-04-05 US disclosed
US-3974123-A Dyes for thermoplastics BASF AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed
US-3950321-A POLYESTERS BASF AKTIENGESELLSCHAFT (DT) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140349969-A1 COMPOUNDS AND METHODS FOR TREATING PAIN TRPV1, ACHE, OPRL1 MEN1 3678/4885KMT2A 2963/4885MAPT 898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.