Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720606 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPK1LMNACYP3A4CA2 | |
| SCHEMBL5720616 | 0.79 | KMT2A (0.51) | ALDH1A1MAPK1LMNATSHRTDP1 | |
| SCHEMBL5720585 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPK1LMNACYP3A4CA2 | |
| SCHEMBL12311743 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPK1LMNACYP3A4CA2 | |
| SCHEMBL15473403 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MAPK1LMNACYP3A4CA2 | |
| SCHEMBL8656363 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPK1LMNACYP3A4CA2 | |
| SCHEMBL2782346 | 0.75 | ALDH1A1 (0.61) | ALDH1A1MAPK1LMNACYP3A4CA2 | |
| SCHEMBL35833 | 0.74 | ALDH1A1 (0.56) | ALDH1A1MAPK1LMNACYP3A4CA2 | |
| SCHEMBL13620917 | 0.74 | ALDH1A1 (0.51) | ALDH1A1MAPK1LMNACYP3A4CA2 | |
| SCHEMBL23870712 | 0.74 | ALDH1A1 (0.54) | ALDH1A1MAPK1LMNACYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474098-B1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP ASSETS BV (NL) | 2006-08-02 | — | — | EP | claimed |