Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720606 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPK1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL4345694 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPK1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5720585 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPK1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL5720659 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPK1LMNAKDM4EMAPT | |
| SCHEMBL14447733 | 0.74 | MAPT (0.44) | ALDH1A1MAPK1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL13223786 | 0.74 | MAPT (0.47) | ALDH1A1MAPK1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL4333847 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MAPK1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL14448679 | 0.72 | MAPT (0.44) | ALDH1A1MAPK1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL8653520 | 0.72 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2MAPTKMT2A | |
| SCHEMBL13223784 | 0.70 | MAPT (0.43) | ALDH1A1MAPK1KDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719690-A | Photorefractive glass article | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |