Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720606 | 0.93 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL4333847 | 0.90 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL4337616 | 0.84 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL8656363 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL5720659 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPK1KDM4ECYP3A4 | |
| SCHEMBL5720589 | 0.77 | MMP9 (0.37) | ALDH1A1LMNAMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL8653520 | 0.74 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2HPGDNPSR1 | |
| SCHEMBL12311743 | 0.70 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPK1KDM4ECYP3A4 | |
| SCHEMBL15473403 | 0.70 | ALDH1A1 (0.63) | ALDH1A1LMNAMAPK1CYP3A4CA2 | |
| SCHEMBL2782346 | 0.69 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPK1CYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474098-B1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP ASSETS BV (NL) | 2006-08-02 | — | — | EP | claimed |
| EP-1474098-A1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP Assets B.V. (NL) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068183-A1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP ASSETS B.V. (NL) | 2003-08-21 | — | — | WO | disclosed |