Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 13/20 | 0.74 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.62 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122773 | 0.93 | GPR132 (0.63) | GPR132CMKLR2CMKLR1PTPN1GPR34 | |
| SCHEMBL27638045 | 0.89 | GPR132 (0.93) | GPR132CMKLR2CMKLR1PTPN1GPR34 | |
| SCHEMBL1122810 | 0.89 | GPR132 (0.93) | GPR132CMKLR2CMKLR1PTPN1GPR34 | |
| SCHEMBL1123644 | 0.89 | GPR132 (0.93) | GPR132CMKLR2CMKLR1PTPN1GPR34 | |
| SCHEMBL1123646 | 0.89 | GPR132 (0.93) | GPR132CMKLR2CMKLR1PTPN1GPR34 | |
| SCHEMBL27638081 | 0.87 | GPR132 (0.89) | GPR132CMKLR2CMKLR1PTPN1GPR34 | |
| SCHEMBL1122680 | 0.87 | GPR132 (0.89) | GPR132CMKLR2CMKLR1PTPN1GPR34 | |
| SCHEMBL27638093 | 0.87 | GPR132 (0.80) | GPR132CMKLR2CMKLR1PTPN1GPR34 | |
| SCHEMBL1123130 | 0.87 | GPR132 (0.80) | GPR132CMKLR2CMKLR1PTPN1GPR34 | |
| SCHEMBL1123605 | 0.86 | GPR132 (0.87) | GPR132CMKLR2CMKLR1PTPN1GPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-A2 | NEW BENZAMIDES AS PPATY MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110983-A2 | NEW BENZAMIDES AS PPARϒ MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-12-23 | — | — | WO | disclosed |