Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021731 | 1.00 | CNR2 (0.41) | CNR2CNR1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL28111340 | 0.98 | CNR2 (0.40) | CNR2CNR1OPRM1OPRD1OPRK1 | |
| SCHEMBL7020161 | 0.98 | CNR2 (0.40) | CNR2CNR1OPRM1OPRD1OPRK1 | |
| SCHEMBL15665283 | 0.92 | CNR2 (0.35) | CNR2CNR1ARPOLB | |
| SCHEMBL16323018 | 0.92 | CNR2 (0.35) | CNR2CNR1ARPOLB | |
| SCHEMBL15665554 | 0.92 | CNR2 (0.35) | CNR2CNR1ARPOLB | |
| SCHEMBL31384866 | 0.90 | CNR2 (0.35) | CNR2CNR1ALDH1A1EPHX1TSHR | |
| SCHEMBL28133681 | 0.83 | CNR2 (0.43) | CNR2CNR1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5616564 | 0.83 | ALDH1A1 (0.42) | CNR2CNR1KDM4EALDH1A1 | |
| SCHEMBL5721034 | 0.83 | CNR2 (0.46) | CNR2CNR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4493828-A | Use of thyrotropin releasing hormone and related peptides as poultry growth promotants | MERCK & CO., INC. (US) | 1985-01-15 | — | — | US | claimed |
| US-20140127762-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALPHA-SUBSTITUTED PROLINE | API CORPORATION (JP) | 2014-05-08 | — | — | US | disclosed |
| US-4493828-A | Use of thyrotropin releasing hormone and related peptides as poultry growth promotants | MERCK & CO., INC. (US) | 1985-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127762-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALPHA-SUBSTITUTED PROLINE | PREP, NPEPPS, DNPEP | CNR2 3201/4885CNR1 2957/4885OPRM1 3962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.