Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.40 |
| ▸ | CNR1 | P21554 | 5/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10979486 | 0.98 | CNR2 (0.41) | CNR2CNR1OPRM1OPRD1OPRK1 | |
| SCHEMBL7021731 | 0.98 | CNR2 (0.41) | CNR2CNR1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL28111340 | 0.96 | CNR2 (0.40) | CNR2CNR1OPRM1OPRD1OPRK1 | |
| SCHEMBL15665554 | 0.94 | CNR2 (0.35) | CNR2CNR1POLBARELANE | |
| SCHEMBL15665283 | 0.94 | CNR2 (0.35) | CNR2CNR1POLBARELANE | |
| SCHEMBL16323018 | 0.94 | CNR2 (0.35) | CNR2CNR1POLBARELANE | |
| SCHEMBL31384866 | 0.88 | CNR2 (0.35) | CNR2CNR1EPHX1 | |
| SCHEMBL29431204 | 0.85 | KDM4E (0.35) | CNR2CNR1POLBEPHX1AR | |
| SCHEMBL5721034 | 0.85 | CNR2 (0.46) | CNR2CNR1POLB | |
| SCHEMBL5616564 | 0.85 | ALDH1A1 (0.42) | CNR2CNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |