SCHEMBL5721171

SCHEMBL5721171

CCc1ccccc1-c1c(-c2ccccc2)ccc2c1C=C(C(C)CC)[CH]2

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MME P08473 1/20 0.32
ACE P12821 1/20 0.32
CPA1 P15085 1/20 0.32
ACE2 Q9BYF1 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
PDCD1 Q15116 1/20 0.30
CD274 Q9NZQ7 1/20 0.30
PTPN5 P54829 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5721854 0.90 TRPA1 (0.31)
SCHEMBL5721689 0.87 PDK2 (0.30)
SCHEMBL5721937 0.86 MME (0.31) MMEACECPA1ACE2KMT2A
SCHEMBL5721369 0.81 PTPN5 (0.35) KMT2APPARGPPARAPDCD1CD274
SCHEMBL5721244 0.81 DPP4 (0.33) MMEACECPA1ACE2KMT2A
SCHEMBL5721629 0.81 PDCD1 (0.36) KMT2APPARGPPARAPDCD1CD274
SCHEMBL5721470 0.81 KMT2A (0.35) MMEACECPA1ACE2KMT2A
SCHEMBL5721421 0.80
SCHEMBL5721170 0.80
SCHEMBL5721723 0.80 METAP2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1640377-A1 Metallocenes and catalyst compositions derived therefrom Exxonmobil Chemical Patents Inc. (US) 2006-03-29 EP disclosed