Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721234 | 0.90 | TRPA1 (0.33) | DPP4PDCD1CD274PTPN5KMT2A | |
| SCHEMBL5721826 | 0.88 | PDCD1 (0.33) | DPP4PDCD1CD274TRPA1ATR | |
| SCHEMBL5721629 | 0.86 | PDCD1 (0.36) | DPP4PDCD1CD274PTPN5KMT2A | |
| SCHEMBL5721369 | 0.86 | PTPN5 (0.35) | DPP4PDCD1CD274PTPN5KMT2A | |
| SCHEMBL5721411 | 0.84 | PTGS2 (0.32) | DPP4PDCD1CD274KMT2A | |
| SCHEMBL5721322 | 0.84 | PTPN5 (0.30) | PTPN5 | |
| SCHEMBL5609823 | 0.84 | HDAC4 (0.32) | — | |
| SCHEMBL5721217 | 0.83 | PTPN5 (0.33) | DPP4PDCD1CD274PTPN5KMT2A | |
| SCHEMBL5721193 | 0.81 | NPC1 (0.37) | ADORA2AADORA1 | |
| SCHEMBL5721171 | 0.81 | MME (0.32) | PDCD1CD274PTPN5KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640377-A1 | Metallocenes and catalyst compositions derived therefrom | Exxonmobil Chemical Patents Inc. (US) | 2006-03-29 | — | — | EP | disclosed |