Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721290 | 0.92 | CTSS (0.31) | CTSSCTSKDRD2HTR2AHTR2C | |
| SCHEMBL5721607 | 0.90 | HTR1D (0.30) | — | |
| SCHEMBL5721651 | 0.90 | RXRA (0.35) | DRD2HTR2AHTR2CRXRARXRB | |
| SCHEMBL5721294 | 0.85 | CTSS (0.34) | CTSSCTSKDRD2HTR2AHTR2C | |
| SCHEMBL5721753 | 0.85 | CTSS (0.34) | CTSSCTSKDRD2HTR2AHTR2C | |
| SCHEMBL5721304 | 0.85 | RXRA (0.35) | CTSSCTSKDRD2HTR2AHTR2C | |
| SCHEMBL5721530 | 0.85 | CTSS (0.31) | CTSSCTSKDRD2HTR2AHTR2C | |
| SCHEMBL5721220 | 0.84 | — | — | |
| SCHEMBL5721199 | 0.83 | CTSS (0.33) | CTSSCTSKDRD2HTR2AHTR2C | |
| SCHEMBL5721623 | 0.82 | RXRA (0.33) | RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640377-A1 | Metallocenes and catalyst compositions derived therefrom | Exxonmobil Chemical Patents Inc. (US) | 2006-03-29 | — | — | EP | disclosed |