Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721753 | 0.95 | CTSS (0.34) | CTSSCTSKDRD2HTR2AHTR2C | |
| SCHEMBL5721613 | 0.94 | CTSS (0.32) | CTSSCTSKDRD2HTR2AHTR2C | |
| SCHEMBL5721553 | 0.94 | RXRA (0.34) | CTSSCTSKDRD2HTR2AHTR2C | |
| SCHEMBL5721530 | 0.89 | CTSS (0.31) | CTSSCTSKDRD2HTR2AHTR2C | |
| SCHEMBL5721567 | 0.87 | IKBKB (0.35) | CTSSCTSKDRD2HTR2AHTR2C | |
| SCHEMBL5721304 | 0.87 | RXRA (0.35) | CTSSCTSKDRD2HTR2AHTR2C | |
| SCHEMBL5721518 | 0.86 | ICMT (0.33) | CTSSCTSKDRD2HTR2AHTR2C | |
| SCHEMBL5721199 | 0.85 | CTSS (0.33) | CTSSCTSKDRD2HTR2AHTR2C | |
| SCHEMBL5721263 | 0.85 | CTSS (0.33) | CTSSCTSKDRD2HTR2AHTR2C | |
| SCHEMBL5721824 | 0.85 | CTSS (0.33) | CTSSCTSKDRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640377-A1 | Metallocenes and catalyst compositions derived therefrom | Exxonmobil Chemical Patents Inc. (US) | 2006-03-29 | — | — | EP | disclosed |