Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29824315 | 1.00 | CA12 (0.42) | CA12CA9MAOACES1PDPK1 | |
| Hydrochloric Acid SCHEMBL2455497 | 0.98 | CA12 (0.41) | CA12CA9MAOACES1PDPK1 | |
| Hydrochloric Acid SCHEMBL7005883 | 0.98 | CA12 (0.41) | CA12CA9MAOACES1PDPK1 | |
| SCHEMBL3099042 | 0.98 | CA12 (0.41) | CA12CA9MAOACES1PDPK1 | |
| Acetamide SCHEMBL1668160 | 0.88 | ALDH1A1 (0.38) | CA12CA9MAOACES1KMT2A | |
| SCHEMBL207528 | 0.79 | CES1 (0.48) | CA12CA9MAOACES1PDPK1 | |
| SCHEMBL4771824 | 0.74 | MAOA (0.34) | MAOACES1MAOBBCHETSHR | |
| SCHEMBL7614336 | 0.74 | MAOA (0.33) | CA12CA9MAOACES1MAOB | |
| SCHEMBL7825908 | 0.74 | MAOA (0.38) | CA12CA9MAOACES1TDP2 | |
| SCHEMBL1550523 | 0.72 | MAOA (0.44) | CA9MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3906 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396191-B1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2026-02-18 | — | — | EP | claimed |
| EP-4653437-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Innovo Therapeutics Inc. (KR) | 2025-11-26 | — | — | EP | claimed |
| US-12448389-B2 | BRM targeting compounds and associated methods of use | PRELUDE THERAPEUTICS INCORPORATED (US) | 2025-10-21 | — | — | US | claimed |
| US-20250241965-A1 | METHOD TO IMPROVE CELL VIABILITY OF CARDIOMYOCYTES | UNIVERSITY OF WASHINGTON (US) | 2025-07-31 | — | — | US | claimed |
| US-20250170121-A1 | ISOQUINOLINONE COMPOUND, AND PREPARATION METHOD AND USE THEREFOR | FUDAN UNIVERSITY (CN) | 2025-05-29 | — | — | US | claimed |
| CN-119751453-A | Preparation method of N-axis chiral isoquinolone derivative | 浙江工业大学 | 2025-04-04 | — | — | CN | claimed |
| CN-119684345-A | Isoquinolinone additive, electrolyte and high-voltage lithium ion battery | 蓝固(常州)新能源有限公司 | 2025-03-25 | — | — | CN | claimed |
| EP-4504909-A1 | METHOD TO IMPROVE CELL VIABILITY OF CARDIOMYOCYTES | University of Washington (US) | 2025-02-12 | — | — | EP | claimed |
| WO-2025024663-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-01-30 | — | — | WO | claimed |
| CN-119350336-A | Isoquinolinone dihydropyridine- [1, 2-alpha ] indole spiro compound, preparation method and application thereof | 南京林业大学 | 2025-01-24 | — | — | CN | claimed |
| US-5670511-A | Indolepiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-09-23 | — | — | US | claimed |
| EP-0770077-A1 | PROCESS FOR THE PREPARATION OF 2-(1-AZABICYCLO(2.2.2)OCT-3-YL) -2,4,5,6-TETRAHYDRO-1H-BENZ(DE)ISOQUINOLIN-1-ONE AND INTERMEDIATE PRODUCT | F. HOFFMANN-LA ROCHE AG (CH) | 1997-05-02 | — | — | EP | claimed |
| US-5589483-A | Isoquinoline poly (ADP-ribose) polymerase inhibitors to treat skin diseases associated with cellular senescence | GERON CORPORATION (US) | 1996-12-31 | — | — | US | claimed |
| US-5510486-A | Process for preparing 2-(1-azabicyclo 2.2.2!oct-3-yl)-2,3,3A,4,5,6-hexahydro-1H-benz de!isoquinolin-1-one | SYNTEX (U.S.A.) INC. (US) | 1996-04-23 | — | — | US | claimed |
| WO-1996001824-A1 | PROCESS FOR THE PREPARATION OF 2-(1-AZABICYCLO(2.2.2)OCT-3-YL) -2,4,5,6-TETRAHYDRO-1H-BENZ(DE)ISOQUINOLIN-1-ONE AND INTERMEDIATE PRODUCT | F. HOFFMANN-LA ROCHE AG (CH) | 1996-01-25 | — | — | WO | claimed |
| EP-0355750-B1 | Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process | WARNER LAMBERT CO (US) | 1995-01-25 | — | — | EP | claimed |
| EP-0482939-A1 | Isoquinolinone derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-04-29 | — | — | EP | claimed |
| US-5004747-A | Isoquinolinones | MAY & BAKER LIMITED (GB) | 1991-04-02 | — | — | US | claimed |
| EP-0355750-A1 | Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process | WARNER-LAMBERT COMPANY (US) | 1990-02-28 | — | — | EP | claimed |
| EP-0326386-A2 | Isoquinolinones | MAY & BAKER LIMITED (GB) | 1989-08-02 | — | — | EP | claimed |