SCHEMBL5721499

SCHEMBL5721499

CC(C)(C)C1=Cc2c(ccc(-c3ccccc3)c2-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)[CH]1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RXRA P19793 3/20 0.35
RXRB P28702 3/20 0.35
RXRG P48443 2/20 0.32
PTAFR P25105 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5721315 0.91 TACR1 (0.40) RXRARXRBRXRG
SCHEMBL5609067 0.86 RXRA (0.35) RXRARXRBRXRGPTAFR
SCHEMBL5721232 0.83 RXRA (0.33) RXRARXRBPTAFR
SCHEMBL5721616 0.83
SCHEMBL5721253 0.83 METAP2 (0.35)
SCHEMBL5721857 0.83 PTGS2 (0.30)
SCHEMBL5721574 0.81 RXRA (0.32) RXRARXRBRXRGPTAFR
SCHEMBL5721863 0.80 RXRA (0.31) RXRARXRBPTAFR
SCHEMBL5721493 0.80 POLB (0.34) RXRARXRBRXRG
SCHEMBL5721851 0.79 CYP1A2 (0.30) RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1640377-A1 Metallocenes and catalyst compositions derived therefrom Exxonmobil Chemical Patents Inc. (US) 2006-03-29 EP disclosed