Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721657 | 0.90 | IKBKB (0.32) | PDE2A | |
| SCHEMBL5721852 | 0.89 | RORC (0.31) | — | |
| SCHEMBL5721614 | 0.87 | IKBKB (0.34) | AKR1C3AKR1C2 | |
| SCHEMBL5721623 | 0.86 | RXRA (0.33) | AKR1C3AKR1C2 | |
| SCHEMBL5721329 | 0.85 | AKR1C3 (0.30) | AKR1C3AKR1C2 | |
| SCHEMBL5721328 | 0.84 | PDE2A (0.33) | PDE2AAKR1C3AKR1C2 | |
| SCHEMBL5721290 | 0.84 | CTSS (0.31) | — | |
| SCHEMBL5721520 | 0.83 | AKR1C3 (0.35) | AKR1C3AKR1C2 | |
| SCHEMBL5721946 | 0.83 | — | — | |
| SCHEMBL5721117 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640377-A1 | Metallocenes and catalyst compositions derived therefrom | Exxonmobil Chemical Patents Inc. (US) | 2006-03-29 | — | — | EP | disclosed |