Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GPX4 | P36969 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14634134 | 0.84 | — | — | |
| SCHEMBL7508450 | 0.84 | HTR7 (0.33) | ALDH1A1 | |
| SCHEMBL5951974 | 0.81 | MAPT (0.38) | TLR8KDM4EMAPTHTTNPC1 | |
| SCHEMBL18760053 | 0.81 | — | — | |
| SCHEMBL1453413 | 0.78 | TLR8 (0.36) | TLR8KDM4EMAPTHTTNPC1 | |
| SCHEMBL7505763 | 0.76 | SMN1; SMN2 (0.36) | TLR8NPC1ALDH1A1RAB9A | |
| SCHEMBL31558464 | 0.76 | SMN1; SMN2 (0.36) | TLR8NPC1ALDH1A1RAB9A | |
| SCHEMBL7505842 | 0.74 | EPHX2 (0.36) | — | |
| SCHEMBL28631957 | 0.73 | CA3 (0.33) | — | |
| SCHEMBL14634135 | 0.73 | ALDH1A1 (0.34) | ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650202-A1 | 4,5-DIHYDRONAPHTHO [1,2-b] THIOPHENE DERIVATIVE | Taisho Pharmaceutical Co. Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |