SCHEMBL5723397

SCHEMBL5723397

Cc1ccc(N(c2ccc(C=NN(CC3CO3)c3ccccc3)cc2)c2ccc(C=NN(CC3CO3)c3ccccc3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.45
MEN1 O00255 8/20 0.45
KMT2A Q03164 8/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
MCL1 Q07820 2/20 0.45
MAPT P10636 7/20 0.40
HSP90AA1 P07900 1/20 0.40
GAA P10253 1/20 0.40
LMNA P02545 5/20 0.39
MAPK1 P28482 3/20 0.39
PKM P14618 1/20 0.38
HPGD P15428 2/20 0.37
G6PC1 P35575 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35
ACHE P22303 1/20 0.34
BACE1 P56817 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
POLB P06746 1/20 0.33
BCHE P06276 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14355044 1.00 ALDH1A1 (0.45) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL14355042 1.00 ALDH1A1 (0.45) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL14254908 0.94 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL4821647 0.94 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL5630076 0.94 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL4821644 0.94 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL5179922 0.86 ALDH1A1 (0.46) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL5858661 0.86 ALDH1A1 (0.46) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL5180365 0.86 ALDH1A1 (0.61) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL14254910 0.85 LMNA (0.44) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1465020-B1 Organophotoreceptor with a charge transport compound having an epoxy group SAMSUNG ELECTRONICS CO LTD (KR) 2006-10-18 EP disclosed
US-7090953-B2 Organophotoreceptor with a charge transport compound having an epoxy group SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-08-15 US disclosed
EP-1465020-A2 Organophotoreceptor with a charge transport compound having an epoxy group Samsung Electronics Co., Ltd. (KR) 2004-10-06 EP disclosed
US-20040161685-A1 Organophotoreceptor with a charge transport compound having an epoxy group S-PRINTING SOLUTION CO., LTD. (KR) 2004-08-19 US disclosed