SCHEMBL4821647

SCHEMBL4821647

C(=NN(CC1CO1)c1ccccc1)c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.47
MEN1 O00255 7/20 0.47
KMT2A Q03164 7/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
MCL1 Q07820 2/20 0.47
MAPT P10636 8/20 0.45
HSP90AA1 P07900 1/20 0.45
GAA P10253 1/20 0.45
LMNA P02545 6/20 0.40
MAPK1 P28482 4/20 0.40
HPGD P15428 2/20 0.38
G6PC1 P35575 2/20 0.37
POLB P06746 3/20 0.36
PKM P14618 1/20 0.36
PSMD14 O00487 1/20 0.36
APAF1 O14727 1/20 0.36
USP2 O75604 1/20 0.36
MMP2 P08253 1/20 0.36
RAD52 P43351 1/20 0.36
CASP6 P55212 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5630076 1.00 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL4821644 1.00 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL14254908 1.00 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL14355042 0.94 ALDH1A1 (0.45) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL14355044 0.94 ALDH1A1 (0.45) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL5723397 0.94 ALDH1A1 (0.45) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL14254910 0.91 LMNA (0.44) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL5179922 0.90 ALDH1A1 (0.46) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL5858661 0.90 ALDH1A1 (0.46) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL5180365 0.89 ALDH1A1 (0.61) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7445877-B2 Charge transport materials having a central disulfane linkage SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-11-04 US disclosed
US-7326506-B2 Bridged charge transport materials having a central sulfur atom linkage SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-02-05 US disclosed
US-7291431-B2 Organophotoreceptor with charge transport compound having an epoxy group SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-11-06 US disclosed
US-7244541-B2 Linked dihydrazone-based charge transport compounds SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-07-17 US disclosed
EP-1519235-B1 Linked dihydrazone-based charge transport compounds SAMSUNG ELECTRONICS CO LTD (KR) 2007-07-11 EP disclosed
EP-1591837-B1 Hydrazone-based charge transport materials SAMSUNG ELECTRONICS CO LTD (KR) 2007-05-09 EP disclosed
EP-1418469-B1 Organophotoreceptor with charge transport compound with hydrazone groups SAMSUNG ELECTRONICS CO LTD (KR) 2007-04-04 EP disclosed
EP-1600821-B1 Bridged charge transport materials having a central sulfur atom linkage SAMSUNG ELECTRONICS CO LTD (KR) 2007-02-28 EP disclosed
US-7169521-B2 Hydrazone-based charge transport materials SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-01-30 US disclosed
US-7118840-B2 Organophotoreceptor with a charge transport material having at least three linked hydrazone groups SAMSUNG ELECTRONICS CO., LTD (CN) 2006-10-10 US disclosed
EP-1519235-A2 Linked dihydrazone-based charge transport compounds Samsung Electronics Co., Ltd. (KR) 2005-03-30 EP disclosed
US-20050058916-A1 Linked dihydrazone-based charge transport compounds S-PRINTING SOLUTION CO., LTD. (KR) 2005-03-17 US disclosed
US-20040152002-A1 Organophotoreceptor with charge transport material having two linked hydrazone groups SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-08-05 US disclosed
EP-1443039-A1 Organophotoreceptor with charge transport material having two linked hydrazone groups Samsung Electronics Co., Ltd. (KR) 2004-08-04 EP disclosed
US-20040106054-A1 Organophotoreceptor with charge transport compound with hydrazone groups S-PRINTING SOLUTION CO., LTD. (KR) 2004-06-03 US disclosed
EP-1420303-A2 Organophotoreceptor with charge transport compound having an epoxy group Samsung Electronics Co., Ltd. (KR) 2004-05-19 EP disclosed
EP-1418469-A2 Organophotoreceptor with charge transport compound with hydrazone groups Samsung Electronics Co., Ltd. (KR) 2004-05-12 EP disclosed
US-20040081903-A1 Organophotoreceptor with charge transport compound having an epoxy group HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2004-04-29 US disclosed
US-20030232264-A1 Linked dihydrazone-based charge transport compounds HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2003-12-18 US disclosed
US-20030232261-A1 Linked dihydrazone-based charge transport compounds S-PRINTING SOLUTION CO., LTD. (KR) 2003-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232264-A1 Linked dihydrazone-based charge transport compounds SLC43A1, SLC26A3, SLC22A8 ALDH1A1 664/4885MEN1 2824/4885KMT2A 2066/4885
US-20030232261-A1 Linked dihydrazone-based charge transport compounds SLC43A1, SLC22A8, SLC6A19 ALDH1A1 523/4885MEN1 3128/4885KMT2A 2819/4885
US-20040081903-A1 Organophotoreceptor with charge transport compound having an epoxy group SLC43A1, SLC46A1, SLC1A2 ALDH1A1 903/4885MEN1 2626/4885KMT2A 3097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.