Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4495546 | 1.00 | MAOA (0.38) | MAOAMAOB | |
| SCHEMBL4495541 | 0.81 | MAOA (0.38) | MAOAMAOB | |
| SCHEMBL5724008 | 0.81 | MAOA (0.38) | MAOAMAOB | |
| SCHEMBL27210001 | 0.72 | MAOA (0.38) | MAOAMAOB | |
| SCHEMBL27230430 | 0.72 | MAOA (0.38) | MAOAMAOB | |
| SCHEMBL67378 | 0.72 | — | — | |
| SCHEMBL7402418 | 0.71 | MAOA (0.40) | MAOAMAOB | |
| SCHEMBL1099753 | 0.69 | — | — | |
| SCHEMBL5544187 | 0.68 | MAOA (0.38) | MAOAMAOB | |
| SCHEMBL8991715 | 0.68 | FDPS (0.36) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003047582-A1 | QUINOLINE DERIVATIVES AS ANTITUMOUR AGENTS | ASTRAZENECA AB (SE) | 2003-06-12 | — | — | WO | claimed |
| EP-1409481-B1 | QUINOLINE DERIVATIVES AND THEIR USE AS TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2006-10-04 | — | — | EP | disclosed |
| WO-2003047582-A1 | QUINOLINE DERIVATIVES AS ANTITUMOUR AGENTS | ASTRAZENECA AB (SE) | 2003-06-12 | — | — | WO | disclosed |