SCHEMBL8991715

SCHEMBL8991715

O=P(O)(O)C(CN1CC=CCC1)P(=O)(O)O

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDPS P14324 3/20 0.36
MAOA P21397 6/20 0.35
ANPEP P15144 2/20 0.34
ERAP2 Q6P179 1/20 0.34
DPP7 Q9UHL4 3/20 0.31
DPP4 P27487 2/20 0.31
MAOB P27338 2/20 0.31
GGPS1 O95749 1/20 0.31
DPP8 Q6V1X1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8597910 0.71 ANPEP (0.61) FDPSANPEPERAP2
SCHEMBL7402418 0.70 MAOA (0.40) MAOADPP7DPP4MAOBDPP8
SCHEMBL8675612 0.70 ANPEP (0.64) FDPSANPEPERAP2
SCHEMBL8991677 0.70 ANPEP (0.64) FDPSANPEPERAP2
SCHEMBL5724010 0.68 MAOA (0.38) MAOAMAOB
SCHEMBL10714751 0.67 FDPS (0.50) FDPSANPEPERAP2GGPS1
SCHEMBL12250791 0.67 FDPS (0.48) FDPSDPP7DPP4DPP8
SCHEMBL8671774 0.65 ANPEP (0.53) FDPSANPEPERAP2GGPS1
SCHEMBL10280098 0.64 MAOA (0.43) MAOADPP7DPP4MAOBDPP8
SCHEMBL8672081 0.64 MEN1 (0.41) ANPEPERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722268-A1 HERBICIDAL AZA BISPHOSPHONIC ACID COMPOSITIONS ZENECA LIMITED (GB) 1996-07-24 EP claimed
WO-1995010188-A2 HERBICIDAL AZA BISPHOSPHONIC ACID COMPOSITIONS ZENECA LIMITED (GB) 1995-04-20 WO claimed