Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 11/20 | 0.77 |
| ▸ | HSD17B2 | P37059 | 10/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.77 |
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | BCR | P11274 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898375 | 0.88 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL8050006 | 0.85 | HSD17B1 (0.94) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL8207447 | 0.84 | HSD17B1 (0.65) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL7129229 | 0.83 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL1180998 | 0.83 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL29832647 | 0.83 | HSD17B1 (0.90) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL29404406 | 0.83 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL70625 | 0.83 | HSD17B1 (1.00) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL2682114 | 0.83 | HSD17B1 (0.90) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 | |
| SCHEMBL3946608 | 0.83 | ALDH1A1 (0.68) | HSD17B1HSD17B2CYP3A4CYP2C9ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551089-A | Estrogen receptor proteolytic modulators and related methods of use | 阿尔维纳斯运营股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| EP-4282861-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | Lapto Co., Ltd. (KR) | 2023-11-29 | — | — | EP | disclosed |
| CN-110612297-B | Estrogen receptor proteolytic modulators and related methods of use | 阿尔维纳斯运营股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| WO-2012017005-A2 | POLYMERS BASED ON BENZODIONES | BASF SE (DE) | 2012-02-09 | — | — | WO | disclosed |