Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5725152 | 0.80 | TAAR1 (0.50) | TAAR1TSHRLMNA | |
| SCHEMBL5663072 | 0.79 | TSHR (0.52) | TAAR1TSHRLMNAACHEBCHE | |
| SCHEMBL6053680 | 0.79 | TSHR (0.52) | TAAR1TSHRLMNAACHEBCHE | |
| SCHEMBL22110750 | 0.75 | TSHR (0.47) | TAAR1TSHRLMNAACHEBCHE | |
| Ethylene SCHEMBL27465209 | 0.74 | LMNA (0.54) | TAAR1TSHRLMNASLC6A2HRH4 | |
| SCHEMBL153049 | 0.73 | LMNA (0.57) | TAAR1TSHRLMNAHRH4HRH3 | |
| SCHEMBL306297 | 0.73 | LMNA (0.57) | TAAR1TSHRLMNAHRH4HRH3 | |
| SCHEMBL715660 | 0.73 | LMNA (0.57) | TAAR1TSHRLMNAHRH4HRH3 | |
| Formaldehyde SCHEMBL28169267 | 0.72 | LMNA (0.56) | TAAR1TSHRLMNASLC6A2HRH4 | |
| SCHEMBL6138329 | 0.72 | TSHR (0.52) | TAAR1TSHRLMNAACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685127-A1 | HETEROCYCLYL-SUBSTITUTED OXETANES FOR THE TREATMENT OF PROLIFERATIVE OR INFECTIOUS DISEASES | The University of Connecticut (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005051944-A1 | HETEROCYCLYL-SUBSTITUTED OXETANES FOR THE TREATMENT OF PROLIFERATIVE OR INFECTIOUS DISEASES | UNIVERSITY OF CONNECTICUT (US) | 2005-06-09 | — | — | WO | disclosed |