Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30226689 | 0.84 | LMNA (0.48) | TAAR1LMNATSHR | |
| SCHEMBL17610572 | 0.81 | LMNA (0.46) | TAAR1LMNATSHR | |
| SCHEMBL5724643 | 0.80 | TAAR1 (0.50) | TAAR1LMNATSHR | |
| SCHEMBL790546 | 0.78 | CYP19A1 (0.46) | TAAR1LMNATSHRCYP3A4MAPT | |
| SCHEMBL30959376 | 0.78 | CYP19A1 (0.52) | TAAR1LMNATSHRCYP3A4MAPT | |
| SCHEMBL24286799 | 0.78 | CYP19A1 (0.49) | TAAR1LMNATSHRCYP3A4MAPT | |
| SCHEMBL20993237 | 0.78 | CYP19A1 (0.49) | TAAR1LMNATSHRCYP3A4MAPT | |
| SCHEMBL18302831 | 0.78 | CYP19A1 (0.49) | TAAR1LMNATSHRCYP3A4MAPT | |
| SCHEMBL15095406 | 0.78 | LMNA (0.48) | TAAR1LMNATSHRCYP3A4MAPT | |
| SCHEMBL15095433 | 0.78 | LMNA (0.48) | TAAR1LMNATSHRCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685127-A1 | HETEROCYCLYL-SUBSTITUTED OXETANES FOR THE TREATMENT OF PROLIFERATIVE OR INFECTIOUS DISEASES | The University of Connecticut (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005051944-A1 | HETEROCYCLYL-SUBSTITUTED OXETANES FOR THE TREATMENT OF PROLIFERATIVE OR INFECTIOUS DISEASES | UNIVERSITY OF CONNECTICUT (US) | 2005-06-09 | — | — | WO | disclosed |