Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.48 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11300900 | 0.88 | LMNA (0.51) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL23622526 | 0.82 | LMNA (0.51) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL16427338 | 0.79 | LMNA (0.48) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL13199362 | 0.78 | LMNA (0.63) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL3567537 | 0.78 | TNKS (0.41) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL22847567 | 0.76 | LMNA (0.60) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL11093962 | 0.76 | LMNA (0.60) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL28409004 | 0.75 | LMNA (0.59) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL10457377 | 0.75 | KDM4E (0.54) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL3558259 | 0.75 | TK1 (0.35) | GRIA2HTTTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719770-A2 | Quinoline derivatives as antibacterials | SMITHKLINE BEECHAM PLC (GB) | 2006-11-08 | — | — | EP | disclosed |
| EP-1320529-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2006-05-24 | — | — | EP | disclosed |
| EP-1320529-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002024684-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-03-28 | — | — | WO | disclosed |