SCHEMBL13199362

SCHEMBL13199362

CCCn1cc(F)c(=O)[nH]c1=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.63
CYP1A2 P05177 4/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 1/20 0.50
GRIA1 P42261 1/20 0.50
GRIA2 P42262 1/20 0.50
GRIA3 P42263 1/20 0.50
GRIA4 P48058 1/20 0.50
GRIK5 Q16478 1/20 0.50
KMT2A Q03164 3/20 0.48
CYP2C19 P33261 3/20 0.45
CYP2C9 P11712 2/20 0.45
GAA P10253 1/20 0.45
MEN1 O00255 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
MAPK3 P27361 1/20 0.44
ASAH1 Q13510 1/20 0.44
SQOR Q9Y6N5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11093962 0.89 LMNA (0.60) LMNACYP1A2SMN1; SMN2KDM4EGRIA1
SCHEMBL10976239 0.88 CYP1A2 (0.60) LMNACYP1A2SMN1; SMN2KDM4EGRIA1
SCHEMBL6760088 0.86 CYP1A2 (0.62) LMNACYP1A2SMN1; SMN2KDM4EGRIA1
SCHEMBL9803023 0.85 LMNA (0.58) LMNACYP1A2SMN1; SMN2KDM4EGRIA1
SCHEMBL22847567 0.83 LMNA (0.60) LMNACYP1A2SMN1; SMN2KDM4EGRIA1
SCHEMBL28409004 0.81 LMNA (0.59) LMNACYP1A2SMN1; SMN2KDM4EGRIA1
SCHEMBL16574245 0.80 LMNA (0.69) LMNACYP1A2SMN1; SMN2KDM4EGRIA1
SCHEMBL13650209 0.80 LMNA (0.50) LMNACYP1A2SMN1; SMN2KDM4EGRIA1
SCHEMBL4118603 0.79 MAPK1 (0.57)
SCHEMBL28820753 0.79 LMNA (0.71) LMNACYP1A2SMN1; SMN2KDM4EGRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9551724-B2 5-fluoro-uracil immunoassay SALADAX BIOMEDICAL, INC. (US) 2017-01-24 US disclosed
US-20100204456-A1 5-Fluoro-Uracil Immunoassay SHANGHAI FOSUN PHARMACEUTICAL (GROUP) CO., LTD. (CN) 2010-08-12 US disclosed
US-7767794-B2 5-fluoro-uracil immunoassay SALADAX BIOMEDICAL INC (US) 2010-08-03 US disclosed
US-20070154972-A1 5-Fluoro-uracil immunoassay SHANGHAI FOSUN PHARMACEUTICAL (GROUP) CO., LTD. (CN) 2007-07-05 US disclosed
US-7205116-B2 5-Fluoro-uracil immunoassay SHANGHAI FOSUN PHARMACEUTICAL (GROUP) CO., LTD. (CN) 2007-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204456-A1 5-Fluoro-Uracil Immunoassay UNG, DPYD, DUT LMNA 4568/4885CYP1A2 3994/4885SMN1; SMN2 3493/4885
US-20070154972-A1 5-Fluoro-uracil immunoassay UNG, DPYD, DUT LMNA 4568/4885CYP1A2 3994/4885SMN1; SMN2 3493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.