Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 8/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5725731 | 0.81 | MEN1 (0.39) | KMT2AMEN1 | |
| SCHEMBL9860239 | 0.79 | MEN1 (0.43) | KMT2AMEN1 | |
| SCHEMBL5725870 | 0.77 | TBXAS1 (0.49) | TBXAS1LTA4HKMT2AMEN1LMNA | |
| SCHEMBL5726588 | 0.77 | MEN1 (0.41) | LTA4HKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL5726536 | 0.77 | DHFR (0.39) | KMT2AMEN1 | |
| SCHEMBL5726456 | 0.77 | KMT2A (0.40) | KMT2AALDH1A1KDM4EMEN1SMN1; SMN2 | |
| SCHEMBL9860185 | 0.77 | MEN1 (0.46) | KMT2AMEN1 | |
| SCHEMBL5738626 | 0.77 | KMT2A (0.44) | LTA4HKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL10923422 | 0.75 | MEN1 (0.47) | KMT2AMEN1 | |
| SCHEMBL9782612 | 0.75 | KMT2A (0.39) | LTA4HKMT2AALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1705169-A2 | Triphenylalkene derivatives and their use as selective estrogen receptor modulators | Hormos Medical Ltd. (FI) | 2006-09-27 | — | — | EP | disclosed |
| EP-1235776-B1 | TRIPHENYLALKENE DERIVATIVES AND THEIR USE AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | HORMOS MEDICAL CORP (FI) | 2006-02-08 | — | — | EP | disclosed |
| US-6875775-B2 | Triphenylalkene derivatives and their use as selective estrogen receptor modulators | HORMOS MEDICAL OY LTD (FI) | 2005-04-05 | — | — | US | disclosed |
| US-6576645-B1 | Such as 3-(4-chloro-1-(4-(2-(2-hydroxyethoxy)ethoxy)phenyl)--2-phenylbut-1 -enyl)phenol; producing tissue specific estro-genic and/or antiestrogenic effect | HORMOS MEDICAL OY LTD (FI) | 2003-06-10 | — | — | US | disclosed |