SCHEMBL5725934

SCHEMBL5725934

CC(C)(C)N(C[C@H]1CO1)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.33
TSHR P16473 2/20 0.31
MAPK1 P28482 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
HTT P42858 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
LMNA P02545 4/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15193782 1.00 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL17094524 1.00 ALDH1A1 (0.33) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL22204441 0.84 ALDH1A1 (0.35) ALDH1A1TSHRMAPK1TDP1
SCHEMBL17475524 0.82 LMNA (0.33) TSHRMEN1KMT2AHTTL3MBTL1
SCHEMBL22204431 0.82
SCHEMBL854782 0.81 ALDH1A1 (0.31) ALDH1A1
SCHEMBL5722071 0.80
SCHEMBL2767957 0.77 SSTR4 (0.35)
SCHEMBL1633115 0.77 SSTR4 (0.35)
SCHEMBL3102536 0.77 SSTR4 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1328509-B1 METHODS OF PRODUCING OXAZOLIDINONE COMPOUNDS PHARMACIA & UPJOHN CO LLC (US) 2006-03-22 EP claimed
US-20150266867-A1 MONOBACTAM ORGANIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS NOVARTIS AG (CH) 2015-09-24 US disclosed
CN-102260252-A Novel oxazolidinone used for treating bacterial infection 2011-11-30 CN disclosed
CN-101993448-A Anti-mycobacteria oxazolidinones used for treating infectious disease SHANGHAI CUMENCOR MEDICAL TECHNOLOGY CO LTD 2011-03-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150266867-A1 MONOBACTAM ORGANIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS MGAM, MGAM2, BPGM ALDH1A1 431/4885TSHR 4851/4885MAPK1 3553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.