Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322428 | 0.73 | LOXL2 (0.42) | CYP1A2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL1281700 | 0.73 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL597601 | 0.72 | — | — | |
| SCHEMBL193032 | 0.69 | HSD17B10 (0.47) | CYP1A2CYP2C9CYP2C19LOXL2 | |
| SCHEMBL27309655 | 0.69 | — | — | |
| SCHEMBL192755 | 0.69 | — | — | |
| SCHEMBL3860830 | 0.68 | HSD17B10 (0.50) | — | |
| Methyl Alcohol SCHEMBL28263563 | 0.68 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9243693 | 0.67 | CPA1 (0.36) | CYP1A2CYP2C19 | |
| SCHEMBL193200 | 0.65 | LPL (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719770-A2 | Quinoline derivatives as antibacterials | SMITHKLINE BEECHAM PLC (GB) | 2006-11-08 | — | — | EP | disclosed |
| EP-1320529-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2006-05-24 | — | — | EP | disclosed |