Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414939 | 0.78 | — | — | |
| SCHEMBL193215 | 0.76 | ALDH1A1 (0.43) | HSD17B10ALDH1A1ACHETDP1LMNA | |
| SCHEMBL18603 | 0.76 | ALDH1A1 (0.43) | HSD17B10ALDH1A1ACHETDP1LMNA | |
| SCHEMBL2906487 | 0.74 | ALDH1A1 (0.41) | HSD17B10ALDH1A1ACHETDP1LMNA | |
| SCHEMBL973063 | 0.74 | ALDH1A1 (0.44) | HSD17B10ALDH1A1ACHETDP1CES1 | |
| SCHEMBL146709 | 0.74 | ALDH1A1 (0.44) | HSD17B10ALDH1A1ACHETDP1LMNA | |
| SCHEMBL3885956 | 0.74 | ALDH1A1 (0.52) | HSD17B10ALDH1A1ACHETDP1LMNA | |
| SCHEMBL218653 | 0.74 | HSD17B10 (0.52) | HSD17B10ALDH1A1ACHETDP1LMNA | |
| SCHEMBL8715421 | 0.72 | ALDH1A1 (0.40) | HSD17B10ALDH1A1ACHETDP1LMNA | |
| SCHEMBL11621790 | 0.71 | HSD17B10 (0.44) | HSD17B10ALDH1A1ACHETDP1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 668 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658933-A | 1,2, 4-triazolol substituted benzenesulfonamide derivatives | 贵阳学院 | 2024-03-08 | — | — | CN | claimed |
| CN-116751244-A | Alpha, beta-unsaturated carbonyl 18 beta-glycyrrhetinic acid derivative, and preparation method and application thereof | 山东大学 | 2023-09-15 | — | — | CN | claimed |
| CN-114478478-B | N- (1- (6- (substituted phenyl) pyridazin-3-yl) piperidin-3-yl) amine/amide derivatives and process for preparing the same | 厦门大学 | 2023-06-13 | — | — | CN | claimed |
| CN-114478478-A | N- (1- (6- (substituted phenyl) pyridazine-3-yl) piperidine-3-yl) amine/amide derivative and preparation method thereof | 厦门大学 | 2022-05-13 | — | — | CN | claimed |
| CN-112694473-A | 7, 9-disubstituted berberine derivative and preparation method and application thereof | 南京林业大学 | 2021-04-23 | — | — | CN | claimed |
| CN-111848548-A | 5-substituted-1, 3, 4-thiadiazole Schiff base derivative and preparation method and application thereof | 天津科技大学 | 2020-10-30 | — | — | CN | claimed |
| CN-106699570-B | Synthesis method of (2-chloro-5-iodophenyl) (4-fluorophenyl) ketone | 山东铂源药业有限公司 | 2020-04-21 | — | — | CN | claimed |
| EP-2044006-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-30 | — | — | EP | claimed |
| US-20170305864-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2017-10-26 | — | — | US | claimed |
| EP-2903440-B1 | HETEROCYCLIC COMPOUNDS AS PEST CONTROLLING AGENTS | BAYER CROPSCIENCE AG (DE) | 2017-09-06 | — | — | EP | claimed |
| EP-0031104-B1 | THIAZOLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-10-23 | — | — | EP | claimed |
| US-4521430-A | VASODILATOR, ANTIISCHEMIC AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1985-06-04 | — | — | US | claimed |
| EP-0141909-A2 | E-Triazolylpentenols, process for their preparation and biocides and plant growth regulators containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-05-22 | — | — | EP | claimed |
| EP-0128462-A1 | Novel benzothiazepine derivatives, processes for preparing the same and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1984-12-19 | — | — | EP | claimed |
| EP-0048548-B1 | PHARMACEUTICAL COMPOSITIONS OF FUNGICIDAL TRIAZOLE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-14 | — | — | EP | claimed |
| EP-0097425-A2 | Fungicidal or plant growth regulating triazolyl ethanols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-01-04 | — | — | EP | claimed |
| US-4370334-A | VASODILATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-01-25 | — | — | US | claimed |
| EP-0048548-A1 | Pharmaceutical compositions of fungicidal triazole derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-03-31 | — | — | EP | claimed |
| EP-0031104-A1 | Thiazolidine compounds, processes for their preparation and pharmaceutical compositions containing them | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1981-07-01 | — | — | EP | claimed |
| US-4129739-A | Amidine compounds | GAF CORPORATION (US) | 1978-12-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305864-A1 | HETEROCYCLIC COMPOUNDS AS PESTICIDES | DDT, ACHE, PTMS | HSD17B10 1198/4885ALDH1A1 2740/4885ACHE 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.