Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 17/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 17/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 17/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 16/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5725406 | 0.80 | OPRM1 (0.38) | OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL5724709 | 0.73 | NPC1 (0.40) | ALDH1A1 | |
| SCHEMBL5368864 | 0.64 | OPRM1 (0.47) | OPRM1OPRK1OPRL1OPRD1ALDH1A1 | |
| SCHEMBL11727598 | 0.63 | OPRL1 (0.62) | OPRM1OPRK1OPRL1OPRD1 | |
| Methane SCHEMBL11728059 | 0.63 | OPRM1 (0.50) | OPRM1OPRK1OPRL1OPRD1ALDH1A1 | |
| SCHEMBL9792723 | 0.61 | OPRM1 (0.51) | OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL21787342 | 0.61 | OPRM1 (0.51) | OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL13163119 | 0.61 | OPRM1 (0.51) | OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL8534618 | 0.60 | OPRM1 (0.46) | OPRM1OPRK1OPRL1OPRD1ALDH1A1 | |
| SCHEMBL11461609 | 0.60 | OPRM1 (0.55) | OPRM1OPRK1OPRL1OPRD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246810-B1 | PIPERIDINYLOXY AND PYRROLIDINYLOXYPHENYL OXAZOLIDINONES AS ANTIBACTERIALS | ORTHO MCNEIL PHARM INC (US) | 2006-05-17 | — | — | EP | disclosed |
| US-6518285-B2 | 4-oxo-5-oxazolidineylmethyl derivatives; antibacterials which are active against numerous multidrug-resistant gram positive organisms | ORTHO MCNEIL PHARMACEUTICAL, INC. | 2003-02-11 | — | — | US | disclosed |
| US-20020103377-A1 | Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103377-A1 | Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials | OXA1L, RPS27L, RPS27 | OPRM1 546/4885OPRK1 1070/4885OPRL1 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.