Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11268886 | 0.98 | OPRM1 (0.44) | OPRM1OPRK1OPRL1OPRD1MEN1 | |
| SCHEMBL24359355 | 0.90 | KMT2A (0.46) | OPRM1OPRK1OPRL1OPRD1MEN1 | |
| SCHEMBL3451288 | 0.90 | KMT2A (0.46) | OPRM1OPRK1OPRL1OPRD1MEN1 | |
| SCHEMBL9682023 | 0.86 | ALDH1A1 (0.47) | OPRM1OPRK1OPRL1OPRD1ALDH1A1 | |
| SCHEMBL9683882 | 0.83 | OPRM1 (0.48) | OPRM1OPRK1OPRL1OPRD1KMT2A | |
| SCHEMBL8534954 | 0.83 | OPRM1 (0.47) | OPRM1OPRK1OPRL1OPRD1KMT2A | |
| SCHEMBL9684251 | 0.81 | ALDH1A1 (0.44) | OPRM1OPRK1OPRL1OPRD1KMT2A | |
| SCHEMBL11415783 | 0.81 | MEN1 (0.44) | OPRM1OPRK1OPRL1OPRD1MEN1 | |
| SCHEMBL27402701 | 0.79 | MEN1 (0.51) | OPRM1OPRD1MEN1KMT2A | |
| SCHEMBL25665529 | 0.79 | SLC6A9 (0.46) | OPRM1OPRK1OPRL1OPRD1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817651-A | ANALGESICS, RHEUMATIC DISEASES, ANTIINFLAMMATORY AGENTS | SANOFI (FR) | 1998-10-06 | — | — | US | disclosed |
| US-5607933-A | METHODS FOR TREATMENT OF GLAUCOMA AND FOR RELIEF OF PAIN AND RHEUMATIC AND INFLAMMATORY CONDITIONS BY ADMINISTERING THE INDOLES; N-HETERYL IS 2-PIPERAZINYL | STERLING WINTHROP INC. (US) | 1997-03-04 | — | — | US | disclosed |
| US-5324737-A | Analgesics, antirheumatic and antiinflammatory agents, glaucoma | STERLING WINTHROP INC. (US) | 1994-06-28 | — | — | US | disclosed |
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |
| US-5068234-A | Analgesics, rheumatic diseases, antiinflammatory agents or antiglaucoma | STERLING DRUG INC. (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0444451-A2 | 3-Arylcarbonyl-1H-indoles useful as therapeutic agents | STERLING WINTHROP INC. (US) | 1991-09-04 | — | — | EP | disclosed |
| EP-0114706-B1 | 2-ACETIDINYLACETIC ACID,ITS PREPARATION,COMPOSITIONS CONTAINING IT,AND METHOD OF STERILISING THE ANTHERS OF A PLANT | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-09-09 | — | — | EP | disclosed |
| US-4620866-A | POLLEN STERILIZATION OF WHEAT PLANTS | SHELL OIL COMPANY (US) | 1986-11-04 | — | — | US | disclosed |
| EP-0114706-A1 | 2-Acetidinylacetic acid,its preparation,compositions containing it,and method of sterilising the anthers of a plant | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-08-01 | — | — | EP | disclosed |
| US-4200628-A | ANTIBIOTICS, BACTERICIDES | SHIONOGI & CO., LTD. (JP) | 1980-04-29 | — | — | US | disclosed |
| EP-0001643-A2 | Aminoglycoside derivatives, process for their manufacture, pharmaceutical compositions and carboxylic acids | SHIONOGI & CO., LTD. (JP) | 1979-05-02 | — | — | EP | disclosed |