Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727633 | 0.85 | MAPT (0.49) | — | |
| SCHEMBL5727136 | 0.82 | DHFR (0.40) | DHFRPKM | |
| SCHEMBL9687045 | 0.71 | NOS2 (0.39) | — | |
| SCHEMBL5727329 | 0.70 | DHFR (0.49) | DHFR | |
| SCHEMBL4462978 | 0.70 | ALDH1A1 (0.51) | — | |
| SCHEMBL5725973 | 0.69 | — | — | |
| SCHEMBL5727573 | 0.69 | PIK3CD (0.43) | — | |
| SCHEMBL5726356 | 0.68 | DHFR (0.46) | DHFR | |
| SCHEMBL5727636 | 0.68 | ALDH1A1 (0.49) | — | |
| SCHEMBL5727506 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395568-B1 | 4-AMINOPYRIMIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-11-02 | — | — | EP | claimed |