Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | FADS1 | O60427 | 2/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | DGKZ | Q13574 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727485 | 0.94 | TSHR (0.37) | MGLLMEN1KMT2ATSHRNPSR1 | |
| SCHEMBL4080122 | 0.94 | CNR1 (0.40) | MGLLMEN1KMT2ATSHRNPSR1 | |
| SCHEMBL5727631 | 0.94 | MEN1 (0.37) | MGLLMEN1KMT2ATSHRNPSR1 | |
| SCHEMBL4072255 | 0.93 | MEN1 (0.37) | MGLLMEN1KMT2ATSHRNPSR1 | |
| SCHEMBL5727699 | 0.90 | CNR1 (0.38) | MGLLMEN1KMT2ATSHRNPSR1 | |
| SCHEMBL4684882 | 0.90 | MEN1 (0.36) | MGLLMEN1KMT2ATSHRNPSR1 | |
| SCHEMBL4966303 | 0.88 | MGLL (0.40) | MGLLMEN1KMT2ATSHRNPSR1 | |
| SCHEMBL4787427 | 0.88 | CNR1 (0.36) | MGLLMEN1KMT2ATSHRNPSR1 | |
| SCHEMBL5727486 | 0.86 | MGLL (0.37) | MGLLMEN1KMT2ATSHRNPSR1 | |
| SCHEMBL1569103 | 0.85 | CNR1 (0.41) | MGLLMEN1KMT2ATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636181-A1 | SUBSTITUTED 3-ALKYL AND 3-ALKENYL AZETIDINE DERIVATIVES | Merck & Co., Inc. (US) | 2006-03-22 | — | — | EP | claimed |
| WO-2005000809-A1 | SUBSTITUTED 3-ALKYL AND 3-ALKENYL AZETIDINE DERIVATIVES | MERCK & CO., INC. (US) | 2005-01-06 | — | — | WO | claimed |