Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4072255 | 0.91 | MEN1 (0.37) | MGLLSCN9ASCN5AOPRD1MEN1 | |
| SCHEMBL5727242 | 0.89 | OPRM1 (0.36) | SCN9ASCN5AOPRD1MEN1KMT2A | |
| SCHEMBL5727699 | 0.88 | CNR1 (0.38) | MGLLMEN1KMT2AGLATSHR | |
| SCHEMBL5727552 | 0.88 | SLC6A9 (0.34) | MGLLOPRD1MEN1KMT2AGLA | |
| SCHEMBL5727680 | 0.86 | MGLL (0.41) | MGLLMEN1KMT2AGLATSHR | |
| SCHEMBL5727357 | 0.85 | P2RX7 (0.35) | SCN9ASCN5AOPRD1MEN1KMT2A | |
| SCHEMBL5727485 | 0.85 | TSHR (0.37) | MGLLOPRD1MEN1KMT2AGLA | |
| SCHEMBL4686679 | 0.84 | SLC6A9 (0.34) | SCN9ASCN5AOPRD1MEN1KMT2A | |
| SCHEMBL5727387 | 0.84 | SLC6A9 (0.34) | SCN9ASCN5AOPRD1MEN1KMT2A | |
| SCHEMBL4080122 | 0.84 | CNR1 (0.40) | MGLLMEN1KMT2AGLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636181-A1 | SUBSTITUTED 3-ALKYL AND 3-ALKENYL AZETIDINE DERIVATIVES | Merck & Co., Inc. (US) | 2006-03-22 | — | — | EP | claimed |
| WO-2005000809-A1 | SUBSTITUTED 3-ALKYL AND 3-ALKENYL AZETIDINE DERIVATIVES | MERCK & CO., INC. (US) | 2005-01-06 | — | — | WO | claimed |